HRs for all-cause mortality according to BMI trajectory groups in the Melbourne Collaborative Cohort Study, overall and in never-smokers
BMI trajectory groups | Overall n=(29 881)* | Never-smokers n=(17 475)† | ||||||
Person-years | Deaths | HR | 95% CI | Person-years | Deaths | HR | 95% CI | |
All-cause mortality | ||||||||
TR1 Lower-normal stable | 72 077 | 1162 | 1.00 | 45 432 | 604 | 1.00 | ||
TR2 Higher-normal stable | 141 989 | 2507 | 0.90 | 0.84 to 0.97 | 83 881 | 1220 | 0.96 | 0.87 to 1.07 |
TR3 Normal to overweight | 103 976 | 1826 | 0.96 | 0.89 to 1.04 | 58 515 | 820 | 1.00 | 0.90 to 1.12 |
TR4 Borderline obesity chronic | 11 711 | 280 | 1.16 | 1.01 to 1.33 | 6210 | 120 | 1.25 | 1.02 to 1.53 |
TR5 Normal to class I obesity | 37 235 | 600 | 1.09 | 0.98 to 1.21 | 22 762 | 315 | 1.19 | 1.03 to 1.37 |
TR6 Overweight to class II obesity‡ | 12 357 | 187 | 7838 | 107 | ||||
Age 74 years | 1.31 | 1.11 to 1.54 | 1.42 | 1.13 to 1.78 | ||||
Age 80 years | 1.19 | 1.00 to 1.42 | 1.27 | 1.02 to 1.59 | ||||
Age 85 years | 1.10 | 0.88 to 1.38 | 1.16 | 0.88 to 1.54 |
*Adjusted for age, birth cohort, height, sex, country of birth, SEIFA, highest level of education, smoking status at latest BMI assessment, baseline MDS, alcohol drinking status and physical activity score.
†Adjusted for age, birth cohort, height, sex, country of birth, SEIFA, highest level of education, baseline MDS, alcohol drinking status and physical activity score.
‡The p refers interaction between TR6 and attained age=0.04, tested using likelihood ratio test.
BMI, body mass index; MDS, Mediterranean Diet Score; SEIFA, Socio-Economic Indexes For Areas.