Table 3

Primary and secondary outcomes reported in each study

StudyRestoration successPain/ discomfort/ hypersensitivityAesthetic improvementMineral gainSpace managementAnaesthesia effectivenessPreventive successEfficiencyQuality of lifeGingival and periodontal healthPatient satisfaction
Koch and Garcia-Godoy44 x
Wong and Winter64   x
Lygidakis et al 45 x ♦ ♦
Zagdwon et al 46 x ♦
Kotsanos et al 32 x ♦
Mejàre et al 33 x ♦
Jälevik and Möller47   x
Lygidakis et al 48 x
Baroni and Marchionni49   x
Gaardmand et al 50 x
Özgül et al 65   x
Sheoran et al 66   x
Cabasse et al 51   x
Fragelli et al 52 x
Bekes et al 53   x
DRKS00009760 (2016)  x
Restrepo et al 67   x
Bakkal et al 54   x
de Souza et al 55 x
DRKS00011882 (2017)  x
Fragelli et al 56 x ♦
Sönmez and Saat57 x ♦
Bhandari et al 68   x
Dixit and Joshi58   ♦ x ♦
Folayan et al 59   x
Grossi et al 60 x ♦ ♦
Hasmun et al 69   x
Koleventi et al 61   x
Pasini et al 62   x
NCT03614819 (2018) ♦ ♦ x ♦ ♦ ♦
NCT03760497 (2018) x ♦ ♦ ♦
Dhareula et al 63 x ♦ ♦
NCT03826810 (2019) ♦ x
NCT03870958 (2019)  ♦ x ♦ ♦
NCT03862014 (2019) x

  • x, primary outcome; ♦, secondary outcome