Incidence and HRs of traumatic brain injury by demographic characteristics, comorbidity and follow-up duration among patients with or without migraine
| Variables | Patients with migraine | Patients without migraine | Compared with non-migraine | |||
| TBI | Rate | TBI | Rate | Crude HR* (95% CI) | Adjusted HR* (95% CI) | |
| Overall | 272 | 5.35 | 797 | 1.86 | 2.26 (1.96 to 2.61)† | 1.78 (1.52 to 2.08)† |
| Gender | ||||||
| Men | 84 | 6.46 | 289 | 2.59 | 1.96 (1.53 to 2.51)† | 1.48 (1.13 to 1.95)‡ |
| Women | 188 | 4.97 | 508 | 1.60 | 2.44 (2.05 to 2.89)† | 1.94 (1.60 to 2.36)† |
| Stratified by age | ||||||
| 18–49 | 149 | 4.77 | 422 | 1.66 | 2.29 (1.89 to 2.77)† | 1.85 (1.51 to 2.26)† |
| >50 | 123 | 6.29 | 375 | 2.18 | 2.25 (1.83 to 2.77)† | 1.71 (1.37 to 2.13)† |
| Comorbidity§ | ||||||
| No | 28 | 4.39 | 286 | 1.38 | 2.42 (1.64 to 3.58)† | 2.49 (1.69 to 3.69)† |
| Yes | 244 | 5.49 | 511 | 2.30 | 1.89 (1.61 to 2.20)† | 1.68 (1.42 to 1.98)† |
Rate refers to incidence rate per 1000 person-years.
*Model adjusted for age, gender, income, urbanisation level and relevant comorbidities (hypertension, diabetes mellitus, hyperlipidaemia, coronary artery disease, liver cirrhosis, mental disorders, obesity, tobacco use disorder and alcohol-attributed disease).
†P<0.001.
‡P=0.005.
§Patients with any examined comorbidities, including hypertension, diabetes mellitus, hyperlipidaemia, coronary artery disease, liver cirrhosis, mental disorders, obesity, tobacco use disorder and alcohol-attributed disease, were classified as the comorbidity group.
TBI, traumatic brain injury.