Table 1

Demographic details and spirometric results

Total subjectsAgeMaleCumulative smokingPrior diagnosis of asthmaPrior diagnosis of COPDFEV1 FEV1/FVC
NumberYearsNumber (%)Pack-yearsNumber (%)Number (%)% predicted%
All subjects156653.0±8.7985 (62.9%)14.1±18.646 (2.9%)10 (0.6%)99.6±13.180.1±5.8
Healthy non-smoking subjects*†64653.3±8.8189 (29.3%)0.0±0.117 (2.6%)2 (0.3%)105.5±10.782.3±4.4
COPD defined by fixed ratio8560.4±9.483 (97.6%)36.9±28.15 (5.9%)4 (4.7%)80.2±11.666.0±4.1
Non-COPD smokers81751.9±8.0704 (86.2%)23.1±16.923 (2.8%)4 (0.5%)97.9±11.880.1±4.7
Non-COPD never smokers66453.4±8.9198 (29.8%)0.0±0.018 (2.7%)2 (0.3%)104.2±12.082.0±4.5
COPD defined by LLN3457.7±10.429 (85.3%)31.9±25.82 (5.9%)2 (5.9%)77.3±13.163.0±4.9
Non-COPD smokers86752.4±8.3755 (87.1%)24.2±18.326 (3.0%)6 (0.7%)97.1±12.379.4±5.3
Non-COPD never smokers66553.5±8.9201 (30.2%)0.0±0.018 (2.7%)2 (0.3%)104.1±12.182.0±4.5
  • *FEV1 of >85% predicted and FEV1/FVC of >0.7.

  • †A smoking history of <1 pack-year.

  • COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LLN, lower limit of normal.