Predialysis laboratory parameters of the patients during the 12 months before screening
| Characteristics | Patients (n=578) | RLS patients (n=83) | Non-RLS patients (n=495) | P value |
| Hb concentration (g/L) | 99.40±14.20 | 98.14±13.26 | 99.62±14.36 | 0.380 |
| SF level (µg/L) | 176.72 (95.14–349.59) | 167.16 (89.56–388.15) | 177.48 (95.38–342.34) | 0.971 |
| TFS (%) | 33.02±13.11 | 33.08±12.97 | 32.69±13.98 | 0.807 |
| Kt/V | 1.30±0.24 | 1.29±0.22 | 1.31±0.25 | 0.545 |
| Serum PTH level (ng/L) | 227.00 (123.35–386.73) | 377.30 (230.80–676.30) | 214.30 (117.50–339.50) | <0.001 |
| Hypoalbuminaemia (%) | 370 (64.0) | 47 (56.6) | 323 (65.3) | 0.130 |
| Hyperphosphataemia (%) | 389 (67.3) | 72 (86.7) | 317 (64.0) | <0.001 |
| Hypermagnesaemia (%) | 331 (57.3) | 62 (74.7) | 269 (54.3) | 0.001 |
Hypoalbuminaemia, serum albumin concentration <40 g/L; hyperphosphataemia, serum phosphorus level >1.51 mmol/L; hypermagnesaemia, serum magnesium level more than >1.02 mmol/L.
Hb, haemoglobin; PTH, parathyroid hormone; RLS, restless legs syndrome; SF, serum ferritin; TFS, transferrin saturation.