Table 5

Overview of assessed outcomes based on RE-AIM framework

RE-AIM dimensions
(Level of evaluation)
OutcomesData collection methodsAssessment schedule
Reach
(Individual)
Patients’ characteristics, accrual and retention ratesMedical records, recruitment logs at each centreStudy start: patients’ recruitment and enrolment
Effectiveness
(Individual)
Symptom interference with daily function (activity and affective subdimensions), symptom severity, overall symptom burden, self-efficacy, moodPaper and pencil questionnaires: MDASI, SES6G, LASA Mood ScaleFour measurements over 16 weeks: from BL to t3
Adoption
(Organisational)
Characteristics of participating centre and staff, usual support for SSM, facilitators and barriers for SN©P adoptionFocus group interviews (1), electronic questionnairesStudy start: before patient recruitment starts
Implementation
(Organisational)
(1) Acceptance and appropriateness of nurses’ trainings: training content, nurses’ confidence to integrate SN©P into practice, work-related factors with implementing SN©PPaper and pencil questionnaire,
Work-SoC scale
After first and second training
(2) Nurses’ and physicians’ acceptance of SN©PFocus group interviews (2) and telephone interviewsAfter patients completed all questionnaires (last patient out of study)
(3) Nurses’ fidelity to training manual: key elements applied, patients’ complaints and goals, number and topic of delivered SN©Fyers, additionally delivered information leafletsElectronic questionnaires
Observations
After every semistructured consultations
(4) Patients’ safetyElectronic questionnaires
Focus group interviews (2)
After semistructured consultations
(5) Resources: time needed for trainings, preparing and providing nurse-led consultations, documentationTraining logs
Electronic questionnaires
After training courses and after semistructured consultations
(6) Quality of nursing care estimated by patientsPR-CISE (paper and pencil questionnaires)Three measurements: t1–t3
MaintenanceNot appliedNot appliedNot applied
  • Focus group interviews (1): takes place before patient recruitment starts at the centre; Focus group interviews (2): takes place after last patient is out of study.

  • BL, baseline; MDASI, MD Anderson Symptom Inventory; PR-CISE, patient-reported chemotherapy indicators of symptoms and experiences; RE-AIM, Reach Effectiveness—Adoption Implementation Maintenance; SES6G, Self-Efficacy for Managing Chronic Disease Questionnaire; SSM: Symptom Self-Management; SN©P: Symptom Navi© Program; SN©Flyers: Symptom Navi© Flyers (written information leaflets for patients); Work-SoC, Work-related Sense of Coherence scale.