Comparison of serum Vit B6 and serological metabolism parameters among control, osteopenia and osteoporosis groups
| Characteristics | Women (n=1206) | Men (n=623) | ||||
| Control (n=338) | Osteopenia (n=544) | Osteoporosis (n=324) | Control (n=368) | Osteopenia (n=180) | Osteoporosis (n=75) | |
| Vit B6 (μg/L) | 24.9 (8.90) | 25.1 (11.4) | 25.0 (14.0)*† | 23.3 (12.6) | 23.8 (15.1) | 22.4 (13.3) |
| PINP (ng/mL) | 42.8 (12.8) | 48.6 (23.7)* | 52.3 (17.0)*† | 34.3 (13.9) | 36.4 (12.8) | 41.3 (18.5)* |
| β-CTX (ng/mL) | 0.36 (0.12) | 0.43 (0.17)* | 0.46 (0.16)*† | 0.30 (0.13) | 0.34 (0.15)* | 0.39 (0.18)* |
| OST (ng/mL) | 16.9 (4.88) | 19.2 (6.59)* | 20.7 (7.36)*† | 14.2 (5.46) | 14.9 (5.08) | 16.3 (6.13)* |
| ALP (U/L) | 75.9 (18.3) | 79.3 (19.2)* | 83.2 (21.4)*† | 73.9 (19.9) | 72.1 (18.9) | 78.9 (27.4) |
| P (mmol/L) | 1.15 (0.13) | 1.15 (0.13) | 1.15 (0.13) | 1.01 (0.19) | 1.02 (0.15) | 1.03 (0.19) |
| Ca (mmol/L) | 2.31 (0.09) | 2.31 (0.10) | 2.30 (0.09) | 2.28 (0.09) | 2.28 (0.10) | 2.27 (0.11)‡ |
| 25(OH)D (ng/mL) | 18.7 (6.29) | 18.2 (6.50) | 17.0 (6.38)*† | 19.4 (6.74) | 18.8 (6.35) | 18.1 (6.22) |
| PTH (pmol/L) | 4.28 (1.54) | 4.33 (1.60) | 4.55 (1.88) | 4.14 (1.46) | 4.03 (1.53) | 4.17 (1.67) |
| FGF23 (pg/mL) | 3.58 (7.66) | 3.42 (6.19) | 3.06 (6.89) | 3.79 (6.30) | 3.86 (6.08) | 4.23 (11.3) |
Data are expressed as mean (SD), analysed by Kruskal-Wallis test.
*Compared with control group, p<0.05.
†Compared with osteopenia group, p<0.05.
‡Compared variance among the three group used analysis of variance test.
ALP, alkaline phosphatase; β-CTX, β-C-terminal telopeptide of type I collagen; Ca, calcium; FGF23, fibroblast growth factor 23; OST, osteocalcin; P, phosphorus; PINP, N-terminal propeptide of type I collagen; PTH, parathyroid hormone; Vit B6, vitamin B6.