Cases of CCHD by programme and by pregnancy outcome and clinical presentation, International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR) Critical Congenital Heart Defects (CCHD) Prenatal Diagnosis study 2000–2014*
| Programme – region | Total cases | Pregnancy outcome (%) | Clinical presentation (%) | |||||
| LB | SB | TOPFA | Unknown | Isolated | MCA | Syndromic | ||
| UK-Wales | 1 003 | 81.2 | 2.5 | 16.4 | 0 | 71.6 | 15.5 | 13.0 |
| Germany-Saxony Anhalt | 392 | 84.7 | 2.0 | 13.3 | 0 | 74.7 | 14.0 | 11.2 |
| Netherlands-Northern | 477 | 82.4 | 4.2 | 13.4 | 0 | 74.8 | 11.9 | 13.2 |
| France-Rhone Alps | 820 | 61.7 | 3.2 | 35.1 | 0 | 70.0 | 17.6 | 12.4 |
| Italy-Emilia Romagna | 795 | 79.5 | 0.1 | 20.4 | 0 | 81.3 | 9.4 | 9.3 |
| Italy-Lombardy | 55 | 83.6 | 3.6 | 12.7 | 0 | 85.5 | 7.3 | 7.3 |
| Italy-Tuscany | 451 | 77.2 | 2.2 | 20.6 | 0 | 90.5 | 4.7 | 4.9 |
| Malta | 111 | 97.3 | 2.7 | na | 0 | 79.3 | 9.0 | 11.7 |
| Czech Republic | 4 569 | 68.4 | 0.8 | 23.6 | 7.3 | 89.6 | 5.8 | 4.6 |
| Slovak Republic | 687 | 98.1 | 0.4 | 1.2 | 0.3 | 83.6 | 10.9 | 5.5 |
| Canada | 6 157 | 95.2 | 1.7 | 3.1 | 0 | 79.2 | 11.6 | 9.1 |
| USA-Arkansas | 722 | 97.4 | 2.1 | 0.4 | 0.1 | 67.6 | 20.2 | 12.2 |
| USA-Atlanta | 796 | 92.8 | 2.9 | 3.4 | 0.9 | 67.5 | 13.7 | 18.8 |
| Argentina | 609 | 98.4 | 1.5 | na | 0.2 | 75.5 | 18.4 | 6.1 |
| India-Chennai† | 599 | 6.8 | 0.7 | 35.2 | 57.3 | 82.8 | 15.4 | 1.8 |
*ICBDSR programmes contributed data for different years within this time period (see table 1).
†India-Chennai is a prenatal programme, and only includes congenital heart defects that are prenatally diagnosed
CCHD, critical congenital heart defects; LB, live births; MCA, multiple congenital anomalies; na, not available; SB, stillbirths; TOPFA, termination of pregnancy for fetal anomaly.