Absolute mean decade-specific FEV1 function decline rates (mL/year) | ||||||
Study ID | Sample size (n) | Baseline age (years) | ||||
30–39 | 40–49 | 50–59 | 60–69 | 70–79 | ||
Burchfiel, 199522* | Male (1248) | −19.5† | −21.6 | −25.0 | ||
Burrows, 198623 | Male (158) | 2.83 | −3.01 | −8.85 | −14.69 | −20.53 |
Female (308) | 2.73 | −2.51 | −7.76 | −13.01 | −18.26 | |
Pearson, 199828 | Female (82) | −23.8 | −33.4 | −30 | −23.4 | −25.8 |
Male (91) | −34 | −34 | −34 | −34 | −34 |
The estimates from Burrows were derived from formulae modelling change in FEV1 with age. See online supplementary file 3 for calculations.
*Estimates adjust for covariates including height and age.
†Includes participants aged 45–49 years.
FEV1, forced expiratory volume in 1 s.