Responder analysis: baseline characteristics of patients who had AQLQ data at BT baseline and 12-month follow-up (a responder is defined here as having >=0.5 increase in AQLQ at 12-month follow-up compared with BT baseline). Data shown as mean (SD) or median [min, LQ, UQ, max].
| Characteristic | Responders (n=18) | Non-responders (n=10) |
| Age at first BT (years) | 35.78 (8.7) n=18 | 50.4 (11.0) n=10 |
| Female (%) | 61.1 n=18 | 60.0 n=10 |
| BMI (kg/m2) | 27.7 (5.2) n=17 | 33.23 (10.7) n=10 |
| Non-smoker/Ex-smoker (%) | 100.0 n=17 | 88.9 n=9 |
| FEV1 (% predicted) | 65.9 (22.1) n=18 | 62.3 (19.1) n=10 |
| Eosinophil count (blood) | 0.29 (0.25) n=13 | 0.51 (0.39) n=8 |
| AQLQ score | 3.48 (1.19) n=18 | 3.59 (1.02) n=10 |
| EQ-5D score | 0.54 (0.42) n=11 | 0.58 (0.39) n=9 |
| ACQ score | 3.59 (1.25) n=14 | 3.07 (0.71) n=9 |
| HADS score (Anxiety) | 6.20 (5.53) n=15 | 10.33 (5.29) n=9 |
| HADS score (Depression) | 4.53 (5.40) n=15 | 7.78 (5.04) n=9 |
| Rescue steroid courses (previous year) | 5 [0,2,6,12] n=17 | 2 [0,1.25,3,7] n=10 |
| Unscheduled healthcare* (previous year) | 4.0 [0,1,6,12] n=16 | 3 [0,2,5,10] n=9 |
| Hospital admissions (previous year) | 1.5 [0,0,3.25,10] n=16 | 0 [0,0,1.5,4] n=10 |
| Days lost from work or school (previous year) | 0 [0,1,5,15] n=9 | 3.5 [0,0,9,15] n=4 |
*Includes visits to A&E, GP and asthma clinic.