Intraoperative | Intervention | Rescue 1 | Rescue 2 | Rescue 3 |
Dexamethasone | Chewing gum | Ondansetron 0.15 mg/kg (max: 4 mg) | Droperidol 10 mcg/kg (max: 0.625 mg) | Promethazine 0.2 mg/kg (max: 6.25 mg) |
Ondansetron 4 mg | Droperidol 10 mcg/kg (max: 0.625 mg) | Promethazine 0.2 mg/kg (max: 6.25 mg) | Metoclopramide 0.5 mg/kg (max: 20 mg) | |
Dexamethasone+droperidol | Chewing gum | Ondansetron 0.15 mg/kg (max: 4 mg) | Promethazine 0.2 mg/kg (max: 6.25 mg) | Metoclopramide 0.5 mg/kg (max: 20 mg) |
Ondansetron 4 mg | Promethazine 0.2 mg/kg (max: 6.25 mg) | Metoclopramide 0.5 mg/kg (max: 20 mg) | Propofol 0.3 mg/kg (max: 20 mg) |
All medications apart from propofol can be administered on the ward if patient is discharged from PACU <2 hours postrandomisation, still within the observation period. All medications administered intravenously.