Baseline characteristics of residents with or without HUA
| Total (n=11 488) | HUA (n=4547) | No HUA (n=6941) | P value | |
| Clinical characteristics | ||||
| Male (n, %) | 4047 (35.2) | 1814 (39.9) | 2233 (32.2) | <0.01 |
| Age (years) | 58.22±11.74 | 59.98±11.44 | 57.06±11.79 | <0.01 |
| Urban (n, %) | 5403 (46.9) | 2210 (48.6) | 3193 (46.0) | 0.01 |
| Systolic BP (mm Hg) | 130.51±20.52 | 134.16±20.39 | 128.13±20.25 | |
| Diastolic BP (mm Hg) | 80.70±11.61 | 82.30±11.60 | 79.62±11.49 | <0.01 |
| Non-valvular AF (n, %) | 144 (1.3) | 91 (2.0) | 53 (0.8) | <0.01 |
| Hypertension (n, %) | 3377 (29.4) | 1744 (38.4) | 1633 (23.5) | <0.01 |
| Diabetes mellitus (n, %) | 1050 (9.1) | 528 (11.6) | 522 (7.5) | <0.01 |
| Elevated BP (n, %)* | 6698 (58.3) | 3092 (68.0) | 3606 (52.0) | <0.01 |
| BMI (kg/m2) | 24.01±3.55 | 25.08±3.55 | 23.32±3.37 | <0.01 |
| Abdominal circumference (cm) | 84.41±10.10 | 87.69±9.61 | 82.26±9.83 | <0.01 |
| Male | 84.41±10.11 | 87.71±9.63 | 82.26±9.83 | <0.01 |
| Female | 82.76±9.98 | 86.36±9.64 | 80.66±9.56 | <0.01 |
| Central obesity (n, %)† | 6183 (53.8) | 2984 (65.6) | 3199 (46.1) | <0.01 |
| Heart failure (n, %) | 114 (1.0) | 50 (1.1) | 64 (0.9) | 0.39 |
| Stroke/TIA (n, %) | 274 (2.4) | 128 (2.8) | 146 (2.1) | 0.02 |
| Alcohol consumption (n, %) | 2467 (21.5) | 1060 (23.3) | 1391 (20.0) | <0.01 |
| Smoking (n, %) | 2451 (21.3) | 1114 (24.5) | 1353 (19.5) | <0.01 |
| Laboratory examinations | ||||
| HGB (g/L) | 138.74±14.07 | 140.14±14.11 | 137.83±13.97 | <0.01 |
| PLT (109/L) | 243.78±60.67 | 245.42±61.76 | 242.71±59.93 | 0.019 |
| RBC (1012/L) | 4.76±0.64 | 4.80±0.65 | 4.73±0.63 | <0.01 |
| HDL cholesterol(mmol/L) | 1.49±0.55 | 1.36±0.51 | 1.58±0.56 | <0.01 |
| Reduced HDL cholesterol (n, %)‡ | 2589 (22.5) | 1369 (30.1) | 1220 (17.6) | <0.01 |
| LDL (mmol/L) | 3.64±1.03 | 3.72±1.04 | 3.58±1.01 | <0.01 |
| CHOL (mmol/L) | 5.486±1.13 | 5.57±1.17 | 5.42±1.11 | <0.01 |
| TG (mmol/L) | 1.696±1.43 | 1.47±1.06 | 2.05±1.18 | <0.01 |
| Raised TG level (n, %)§ | 3787 (33.0) | 2140 (47.1) | 1647 (23.7) | <0.01 |
| FPG (mmol/L) | 5.586±1.57 | 5.69±1.52 | 5.51±1.60 | <0.01 |
| Elevated FPG (n, %)¶ | 3375 (29.4) | 1653 (36.4) | 1722 (24.8) | <0.01 |
| Uric acid (μmol/L) | 367.20±98.39 | 460.60±72.77 | 306.01±55.62 | <0.01 |
| Male | 367.00±98.30 | 460.60±72.70 | 306.01±55.63 | <0.01 |
| Female | 340.76±89.40 | 434.37±64.43 | 286.30±46.52 | <0.01 |
| Creatinine (μmol/L) | 76.89±25.45 | 83.78±33.25 | 72.36±17.22 | <0.01 |
*Elevated BP was defined as systolic BP >130 or diastolic BP >85 mm Hg or history of hypertension.
†Central obesity was defined as waist circumference >85 cm for men and >80 cm for women.
‡Reduced HDL was defined as HDL <40 mg/dL (1.03 mmol/L) in men or <50 mg/dL (1.29 mmol/L) in women or specific treatment for this lipid abnormality.
§Raised TG level was defined as TG >150 mg/dL (1.7 mmol/L) or specific treatment for this lipid abnormality.
¶Elevated FPG was defined as fasting plasma glucose >100 mg/dL (5.6 mmol/L) or previously diagnosed type 2 diabetes.
AF, atrial fibrillation; BMI, body mass index; BP, blood pressure; CHOL, cholesterol; FPG, fasting plasma glucose; HDL, high-density lipoprotein; HGB, haemoglobin; HUA, hyperuricaemia; LDL, low-density lipoprotein; PLT, platelet; RBC, red blood cell; TG, triglycerides; TIA, transient ischaemic attack.