Table 1

Baseline characteristics of residents with or without HUA

Total
(n=11 488)
HUA
(n=4547)
No HUA
(n=6941)
P value
Clinical characteristics
 Male (n, %)4047 (35.2)1814 (39.9)2233 (32.2)<0.01
 Age (years)58.22±11.7459.98±11.4457.06±11.79<0.01
 Urban (n, %)5403 (46.9)2210 (48.6)3193 (46.0)0.01
 Systolic BP (mm Hg)130.51±20.52134.16±20.39128.13±20.25
 Diastolic BP (mm Hg)80.70±11.6182.30±11.6079.62±11.49<0.01
 Non-valvular AF (n, %)144 (1.3)91 (2.0)53 (0.8)<0.01
 Hypertension (n, %)3377 (29.4)1744 (38.4)1633 (23.5)<0.01
 Diabetes mellitus (n, %)1050 (9.1)528 (11.6)522 (7.5)<0.01
 Elevated BP (n, %)*6698 (58.3)3092 (68.0)3606 (52.0)<0.01
 BMI (kg/m2)24.01±3.5525.08±3.5523.32±3.37<0.01
 Abdominal circumference (cm)84.41±10.1087.69±9.6182.26±9.83<0.01
  Male84.41±10.1187.71±9.6382.26±9.83<0.01
  Female82.76±9.9886.36±9.6480.66±9.56<0.01
 Central obesity (n, %)†6183 (53.8)2984 (65.6)3199 (46.1)<0.01
 Heart failure (n, %)114 (1.0)50 (1.1)64 (0.9)0.39
 Stroke/TIA (n, %)274 (2.4)128 (2.8)146 (2.1)0.02
 Alcohol consumption (n, %)2467 (21.5)1060 (23.3)1391 (20.0)<0.01
 Smoking (n, %)2451 (21.3)1114 (24.5)1353 (19.5)<0.01
Laboratory examinations
 HGB (g/L)138.74±14.07140.14±14.11137.83±13.97<0.01
 PLT (109/L)243.78±60.67245.42±61.76242.71±59.930.019
 RBC (1012/L)4.76±0.644.80±0.654.73±0.63<0.01
 HDL cholesterol(mmol/L)1.49±0.551.36±0.511.58±0.56<0.01
 Reduced HDL cholesterol (n, %)‡2589 (22.5)1369 (30.1)1220 (17.6)<0.01
 LDL (mmol/L)3.64±1.033.72±1.043.58±1.01<0.01
 CHOL (mmol/L)5.486±1.135.57±1.175.42±1.11<0.01
 TG (mmol/L)1.696±1.431.47±1.062.05±1.18<0.01
 Raised TG level (n, %)§3787 (33.0)2140 (47.1)1647 (23.7)<0.01
 FPG (mmol/L)5.586±1.575.69±1.525.51±1.60<0.01
 Elevated FPG (n, %)¶3375 (29.4)1653 (36.4)1722 (24.8)<0.01
 Uric acid (μmol/L)367.20±98.39460.60±72.77306.01±55.62<0.01
  Male367.00±98.30460.60±72.70306.01±55.63<0.01
  Female340.76±89.40434.37±64.43286.30±46.52<0.01
 Creatinine (μmol/L)76.89±25.4583.78±33.2572.36±17.22<0.01
  • *Elevated BP was defined as systolic BP >130 or diastolic BP >85 mm Hg or history of hypertension.

  • †Central obesity was defined as waist circumference >85 cm for men and >80 cm for women.

  • ‡Reduced HDL was defined as HDL <40 mg/dL (1.03 mmol/L) in men or <50 mg/dL (1.29 mmol/L) in women or specific treatment for this lipid abnormality.

  • §Raised TG level was defined as TG >150 mg/dL (1.7 mmol/L) or specific treatment for this lipid abnormality.

  • ¶Elevated FPG was defined as fasting plasma glucose >100 mg/dL (5.6 mmol/L) or previously diagnosed type 2 diabetes.

  • AF, atrial fibrillation; BMI, body mass index; BP, blood pressure; CHOL, cholesterol; FPG, fasting plasma glucose; HDL, high-density lipoprotein; HGB, haemoglobin; HUA, hyperuricaemia; LDL, low-density lipoprotein; PLT, platelet; RBC, red blood cell; TG, triglycerides; TIA, transient ischaemic attack.