Table 2

Comparisons in the cumulative incidence and prevalence of episodes of antidepressant use in adults ≥65 years between regions and countries

Elderly populationCanadaUSAUKTaiwan
Total elderly populationOntario sample
(Admin. data)*†
Montreal sample
(Admin. data)*†
Quebec city and Montreal
(EMR data)‡
Boston
(EMR data)‡
CPRD sample
(EMR data)†‡
NHIRDB
(Admin. data)*
405 141120 77728 27383 394241 339103 400
All users of antidepressants§
 No of users108 57723 422445017 35924 85824 239
 Prevalence in elderly (%)26.819.415.720.810.323.4
New episodes of antidepressant use¶
 Number of new users60 36613 303130810 13115 86817 580
 Incidence in elderly (%)14.911.04.612.26.617.0
 Age-standardised -incidence (%)15.312.14.712.36.6 (reference)18.6
 Sex-standardised incidence (%)14.911.04.612.16.6 (reference)17.0
Demographics
 Between 65 and 74 years old32 115 (53.2%)5713 (42.9%)699 (53.4%)5826 (57.5%)7129 (44.9%)8811 (50.1%)
 ≥75 years28 251 (46.8%)7590 (57.1%)609 (46.6%)4305 (42.5%)8739 (55.1%)8769 (49.9%)
 Female36 884 (61.1%)8986 (67.5%)853 (65.2%)6136 (60.6%)10 045 (63.3%)9539 (54.3%)
  • *Administrative data are retrieved from population-based health insurance claims for medical visits and prescriptions.

  • †Ontario represents a 20% random sample of elderly, Montreal represents a 25% annual random sample of Montreal residents and the UK represents a 10% random sample of elderly in the CPRD.

  • ‡EMR data are extracted from primary care clinic electronic health records in the USA (Partners), Quebec (MOXXI) and the UK (Clinical Practice Research Database).

  • §All users include persons with an active prescription or dispensed supply of antidepressants between 2007 and 2008 as well as all new users between the period 2009 and 2014.

  • ¶New episodes of use of antidepressants were defined as no prescription or dispensing of an antidepressant in the 2 years prior to the first antidepressant in the period N2009–2014.

  • CPRD, Clinical Practice Research Datalink; EMR, electronic medical record; MOXXI, Medical Office of the 21stst Century; NHIRDB, National Health Insurance Research Database.