Table 3

Time points of the proposed study

Time pointStudy period
Week 0Week 1Week 2Week 3Week 4Week 5Week 63 months6 months9 months12 months
Screening and enrolment
 Informed consent form
 Vital signs
 Medical history
 NRS (neck and arm)
 Eligibility for study
 C-spine X-ray
 Credibility and expectancy
 Doin with acupunctureTwo times/week
 Acupuncture aloneTwo times/week
 Symptoms and medication changes
 NRS (neck and arm)
 VAS (neck and arm)
 Physical examination
 Economic evaluation question (medical costs)
 Economic evaluation question (time-related costs)
 Economic evaluation question (lost productivity costs)
 Adverse eventsEvery visit
  • EQ-5D-5L, EuroQol-5 Dimension; EQ-VAS, the EuroQol Visual Analogue Scale; NDI, Neck Disability Index; NPQ, Northwick Park neck pain Questionnaire; NRS, Numeric Rating Scale; PGIC, Patient Global Impression of Change; SF-12, the Short Form Health Survey 12; VAS, Visual Analogue Scale.