Table 1

Standard Protocol Items: Recommendations for Interventional Trials flowchart—schedule of enrolment, interventions and assessments

TimepointStudy period
−t1 0t0 t1 t2 t3-5 t6
 Eligibility screenX
 Informed consentX
 Whole-body vibration training (12 weeks) Embedded Image
 Control group
  (12 weeks)
Embedded Image
  (12 weeks, no training, both groups)
Embedded Image
 Anamnesis (entity, stadium, pretreatment, prediseases, CIPN relevant medication, allergies, neurological and social anamnesis)X
 Nerve conduction studiesX
 Reported severity of CIPN-induced symptoms (FACT/GOG-Ntx)XXXXX
 Neurological clinical test batteryXXX
 Static and dynamic postural controlXXX
 Questionnaires (physical activity, EORTC-QLQ-C 30, EORTC-QLQ-CIPN20)XXX
 Visual analogue scale (neuropathic pain, dysesthesias)XXX
  • CIPN, chemotherapy-induced peripheral neuropathy; EORTC-QLQ-C,  European Organization for Research and Treatment of Cancer Quality of Life Questionnaire; EORTC-QLQ-CIPN,  European Organization for Research and Treatment of Cancer peripheral neuropathy questionnaire; FACT/GOG-Ntx, Functional Assessment of Cancer Therapy/Gynaecology Oncology Group—Neurotoxicity.