Cut-off | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | AUC | AUC 95% CI | P values | |
HBP (ng/ml) | ≥103.5 | 67.6 | 82.1 | 71.4 | 79.3 | 0.760 | 0.651 to 0.869 | 0.000 |
SOFA score | ≥5.5 | 83.8 | 41.1 | 48.4 | 79.3 | 0.656 | 0.545 to 0.767 | 0.011 |
PCT (ng/ml) | ≥22.15 | 29.7 | 98.2 | 91.6 | 67.9 | 0.580 | 0.453 to 0.706 | 0.195 |
AUC, area under the receiver operating characteristic curve; HBP, heparin-binding protein; NPV, negative predictive value; PCT, procalcitonin; PPV, positive predictive value.