Table 2

Predictors of 30-day all-cause mortality after first infective endocarditis admission during study period (n=2331)

ParameterUnivariate modelsMultivariate model
HR (95% CI)P valueHR (95% CI)P value
Female sex1.19 (0.93 to 1.53)0.1701.09 (0.84 to 1.40)0.532
Age group (years)<0.0001<0.0001
 18–49ReferenceReference
 50–692.34 (1.55 to 3.58)<0.00012.05 (1.35 to 3.13)0.001
 ≥703.50 (2.35 to 5.22)<0.00012.83 (1.88 to 4.24)<0.0001
Charlson comorbidity index<0.0001<0.0001
 0ReferenceReference
 12.25 (1.67 to 3.02)<0.00012.00 (1.49 to 2.70)<0.0001
 ≥22.83 (2.11 to 3.79)<0.00012.40 (1.79 to 3.23)<0.0001
Prosthetic valve implantation*0.67 (0.36 to 1.26)0.217
Pacemaker operation*1.00 (0.37 to 2.70)0.993
Study year (per 1 year increment)0.98 (0.94 to 1.02)0.280
  • *Within a year prior to endocarditis admission.