Table 3

Timing of individual assessments in the Gut Bugs Trial

Baseline6 weeks12 weeks26 weeks
 Medical history and examination
 Clinic blood pressure
 24-hour ambulatory blood pressure monitoring
 3-day dietary record
 Birmingham IBS
 Bowel movement questionnaire
 Matsuda index
 Fasting lipid profile
 Liver function tests
 hsCRP and uric acid
Stool bacteriology
 Gut microbial composition via 16S rRNA amplicon sequencing
  • ASAQ, Adolescent Sedentary Activity Questionnaire; DXA, dual-energy X-ray absorptiometry; EPOCH, Engagement Perseverance Optimism Connectedness Happiness; HbA1c, glycated haemoglobin; HOMA-IR, homoeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive Protein; IBS, irritable bowel syndrome; IPAQ, International Physical Activity Questionnaire; NZAFFQ, New Zealand Adolescent Food Frequency Questionnaire; PedsQL, Paediatric Quality of Life Inventory.