Table 2

Inclusion and exclusion criteria for recipients in the Gut Bugs Trial

InclusionAged 14–18 years.
Body mass index ≥30 kg/m2.
Postpubertal (Tanner stage 5).
ExclusionGastrointestinal disease (including inflammatory bowel disease or coeliac disease).
Use of regular medications that may influence weight, metabolism or the gut microbiome (including oral oestrogen-containing contraceptives, antidepressants, glucose-lowering drugs, diet drugs, as well as inhaled, topical or oral steroids).
Consumption of probiotics.
Type 1 diabetes, type 2 diabetes or monogenic diabetes
Chronic diseases that could affect the primary outcome (other than obesity-related conditions).
Food allergies.
Allergy to macrogol (active ingredient in the bowel preparation product).
Allergy to any over-the-counter medication.
No antibiotic usage for 3 months prior to trial treatment.