Table 1

Baseline characteristics: demographic and clinical features of spondyloarthritis

CharacteristicSpAnr-axSpAASM-W/FET p value
Age (years), median (IQR)34.7 (29.3–43.5)36.9 (29.2–46.9)36.0 (29.3–44.1) 0.551
GenderMale number (%)131 (53.3)54 (38.6)77 (72.6) <0.001
BMI (kg/m2), median (IQR)24.3 (21.7–27.4)24.8 (21.6–28.2)24.2 (22.6–26.6)0.946
History of smoking
Ever-smoker, number (%)107 (43.7)52 (37.1)55 (52.4)0.138
HLA-B27 positive, number (%)215 (87.4)117 (83.6)98 (92.5)0.051
Disease duration, years (IQR)7.8 (3.1–14.5)5.6 (2.6–12.2)10.2 (5.1–15.5) 0.001
First symptom0.086
Back pain, number (%)195 (79.3)104 (74.3)91 (85.8)
Peripheral arthritis, number (%)27 (11.0)19 (13.6)8 (7.5)
Extra-articular manifestations, number (%)24 (9.8)17 (12.1)7 (6.6)
Family history
First-degree relatives, number (%)86 (35.0)38 (27.1)24 (22.6)0.460
Second-degree relatives, number (%)28 (11.4)18 (12.9)10 (9.4)0.426
History of
Peripheral arthritis, number (%)68 (27.6)50 (35.7)18 (17) 0.001
Hip arthritis, number (%)32 (13.0)12 (8.6)20 (18.9) 0.022
Uveitis, number (%)63 (25.6)39 (27.9)24 (22.6)0.379
IBD, number (%)13 (5.3)9 (6.4)4 (3.8)
Psoriasis, number (%)1 (0.4)0 (0)1 (0.9)
Other, number (%)3 (1.2)1 (0.7)2 (1.9)
Current symptoms
MASES, median (IQR)0.0 (0.0–2.0)0.0 (0.0–2.0)0.0 (0.0–1.3)0.289
SJC, mean (±SD)0.4 (1.4)0.5 (1.5)0.3 (1.4) 0.021
TJC, mean (±SD)0.4 (1.4)0.5 (1.4)0.3 (1.7) 0.015
Current medication
NSAIDs, number (%)126 (51.2)71 (50.7)55 (51.9) 0.898
CsDMARDs, number (%)39 (15.9)26 (18.6)13 (12.3) 0.218
Corticosteroids, number (%)5 (2)2 (1.4)3 (2.8)
BoDMARDs/bsDMARDs, number (%)*6 (2.4)2 (1.4)4 (3.8)
  • *Adalimumab two patients; certolizumab  one patient; golimumab  two patients; infliximab one patient.

  • AS, ankylosing spondylitis; BMI, Body Mass Index; BoDMARDs, biological original disease modifying antirheumatic drugs; bsDMARDs, biosimilar disease modifying antirheumatic drugs; csDMARDs, conventional synthetic disease modifying antirheumatic drugs; IBD, inflammatory bowel disease; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; M-W/FETp, Mann-Whitney/Fisher exact test p value; nr-axSpA, non-radiographic axial spondyloarthritis; NSAIDs, non-steroidal anti-inflammatory drugs; SJC, swollen joint count; SpA, spondyloarthritis; TJC, tender joint count.