Table 6

Clinical Risk factors for GORD with DE: results of the cumulative multivariable logistic regression model

Risk factors (for GORD with DE’s)COR (95% CI)P value*AOR (95% CI)P value†
1. Unhealthy dietary pattern
 Yes 6.034 (1.889 to 19.268)<0.010.474 (0.091 to 2.452)0.003
 No11
2. Nausea/vomiting
 Yes0.349 (0.160 to 0.759)0.0080.256 (0.067 to 0.980)0.047
 No11
3. Xerostomia
 Yes 4.653 (2.426 to 8.923)<0.01 3.005 (1.026 to 8.805)0.045
 No11
4. Ulceration
 Yes 13.725 (5.506 to 34.218)<0.01 6.609 (2.007 to 21.765)0.002
 No11
5. Gingivitis
 Yes 9.038 (4.547 to 17.968)<0.01 7.516 (2.517 to 22.443)<0.01
 No11
6. Angular cheilitis
 Yes 5.190 (2.382 to 11.312)<0.01 4.028 (1.237 to 13.115)0.021
 No11
  • Odds ratios in bold exhibit corresponding clinically significant risk factors, highly associated with Chronic GORD (ie, GORD with DE).

  • CORs (crude ORs) represent a univariate analysis, while AORs (adjusted ORs) represent multivariable analysis (using backward-elimination method).

  • *All significant variables with p<0.05, obtained through univariate analysis (from tables 3 and 5), are computed against dichotomous outcome variable, ‘GORD with DE.’

  • †Using backward selection (likelihood ratio), all 17 variables were entered in multivariable logistic regression model; only 6 of 17 significant variables (from tables 3 and 5), retained significance within the final regression model, which are shown here in this table. This model was tested for discrimination, with an AUROC value of 0.922.

  • AUROC, area under the receiver operating characteristic curve; DE, dental erosions; GORD, gastro-oesophageal reflux disease.