Table 1

Definition of MCI by EADC in 2005 and the instruments and cut-offs used for its assessment in the study

MCI definition criteriaInstrument usedAssessment cut-off adopted in the study
1. Cognitive complaints coming from the patients or their families
2. Reporting of a relative decline in cognitive functioning during the past year by the patient or informant
History from the patient or bystander
3. Cognitive disorders as evidenced by clinical evaluationMalayalam version of Addenbrooke’s Cognitive Examination (m-ACE).47 Score below the cut-off in at least one of the seven cognitive domains assessed.
[One SD below the mean score (of that educational category) was taken as the cut-off for each domain]
4. Absence of major repercussions on daily lifeEveryday Ability Scale for India (EASI)95th percentile of EASI scores of subjects with no subjective or objective cognitive decline in the study sample was taken as cut-off. This was 2; a score up to 2 was taken as normal activities of daily living.
5. Absence of dementiaDSM IV criteriaPatients not satisfying this criteria
  • DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; EADC, European Alzheimer’s Disease Consortium; MCI, mild cognitive impairment.