Table 2

Type of analyser and methodology used for blood biomarker calculation

TestAnalyser/methodLower limit of detectionUpper limit of detection
C reactive proteinSiemens Advia Chemistry XPT, Polyethylene Glycol enhanced immunoturbidimetric assay.
Siemens Advia 1800, Polyethylene Glycol enhanced immunoturbidimetric assay.
5 mg/LDiluted to result
B-type natriuretic peptideSiemens Advia Centaur XPT, two-site sandwich immunoassay using direct chemiluminescent technology.2.0 pg/mL1445 pg/mL
Troponin-IAbbott Architect i2000SR, three-site sandwich immunoassay using direct chemiluminescent technology (CMIA).5.0 ng/L50 000 ng/L
  • The table outlines analyser make, methodology, upper and lower limits of detection as per the University Hospitals of Leicester National Health Service Foundation trust laboratory guidelines.