Table 3

Main study measures in the Prospective Research in Stress-Related Military Operations study over time

	T₀: Predeployment	T₁: 1-month follow-up	T₂: 6-month follow-up	T₃: 1-year follow-up	T₄: 2-year follow-up	T₅: 5-year follow-up	T₆: 10-year follow-up
(Epi) Genetics
Telomere length	Plasma	Plasma	Plasma
DNA methylation	Plasma	Plasma	Plasma
GR and FKBP5 SNPs	Plasma	Plasma	Plasma
mRNA expression PBMCs	Plasma	Plasma	Plasma
Immunology
Leucocyte subpopulations	Plasma	Plasma	Plasma
T-cell cytokine secretion	Plasma	Plasma	Plasma
PBMC glucocorticoid binding	Plasma	Plasma	Plasma
PBMC IL-1β reactivity	Plasma	Plasma	Plasma
Neuroendocrinology
Testosterone	Plasma	Plasma	Plasma
Cortisol	Plasma, salivary	Plasma, salivary	Plasma, salivary
SHBG	Plasma	Plasma	Plasma
Oxytocin	Plasma	Plasma	Plasma
Vasopressin	Plasma	Plasma	Plasma
Neuropeptide Y	Plasma	Plasma	Plasma
GABA	Plasma	Plasma	Plasma
Demographic factors	Self-report	Self-report	Self-report	Self-report	Self-report	Self-report	Self-report, interview
General health and psychological morbidity
Physical health	Self-report	Self-report	Self-report	Self-report	Self-report		Interview
Psychological symptoms	SCL-90-R	SCL-90-R	SCL-90-R	SCL-90-R	SCL-90-R	BSI	SCL-90-R, M.I.N.I. Plus
Depression				CES-D	CES-D	CES-D	CES-D
PTSD	SRIP	SRIP	SRIP	SRIP	SRIP	SRIP	SRIP
Fatigue	CIS-20R	CIS-20R	CIS-20R	CIS-20R	CIS-20R	CIS-20R	CIS-20R
Alcohol use							AUDIT
Burnout	UBOS	UBOS	UBOS
Quality of life							SF-36
Healthcare utilisation						Self-report	Self-report
Production losses						SF-HLQ	SF-HLQ
Life events
Life events				Self-report	Self-report	Self-report	Self-report, interview
Early trauma	ETISR-SF
Personality and coping
Hostility	CMHS	CMHS	CMHS	CMHS	CMHS
Type-D personality	DS-14	DS-14	DS-14	DS-14	DS-14	DS-14
Temperament and character	TCI-SF	TCI-SF	TCI-SF		TCI-SF	TCI-SF	TCI-SF
Anger							STAXI-2
Coping style				Brief-COPE	Brief-COPE	Brief-COPE
Social support
General support						SSL-6	SSL-6
Deployment social support				DRRI-F	DRRI-F
Postdeployment support				DRRI-L	DRRI-L
Deployment experience
Combat exposure		DES					Interview
Traumatic blast						BTBIS
Reintegration after deployment				PDRS	PDRS
Moral injury							MIQ-M
Meaning							ZGL

AUDIT, Alcohol Use Disorders Identification Test30 31; Brief-COPE, Brief COPE Inventory32; BSI, Brief Symptom Inventory4 33; BTBIS, Brief Traumatic Brain Injury Screen34–36; CES-D, Centre for Epidemiologic Studies Depression Scale37; CIS-20R, Checklist Individual Strength10 38; CMHS, Cook-Medley Hostility Scale39 40; DES, Deployment Experience Scale24; DRRI, Deployment Risk and Resilience Inventory41; DS-14, Type-D Scale42; ETISR-SF, Early Trauma Inventory-Self Report43; GR, Glucocorticoid receptor; M.I.N.I. Plus, MINI-International Neuropsychiatric Interview-Plus11; MIQ-M, Moral Injury Questionnaire-Military version44; PBMC, Peripheral blood mononuclear cells; PDRS, PostDeployment Reintegration Scale45; SCL-90-R, Symptom CheckList8 46 47; SF-36, Medical Outcome Study Short-Form Survey48 49; SF-HLQ, Short Form-Health and Labour Questionnaire50 51; SHBG, Sex hormone-binding globulin; SNP, Single nucleotide polymorphism; SRIP, Self-Rating Inventory for PTSD6 7; SSL-6, Social Support List52 53; STAXI-2, State-Trait Anger Expression Inventory-254 55; TCI-SF, Temperament and Character Inventory-Short Form56 57; UBOS, Utrecht Burnout Scale58 59; ZGL, Zingevingslijst.60