Table 2

Components of the clinical decision rules

Coronary artery disease
Gencer rule7
History of CVD	2	Score ranges from 0 to 11 points 0–4 points: low risk 5–7 points: moderate risk 8–11 points: high risk
Age/sex (F ≥65 years or M ≥55 years)	2
Increased pain with exercise	1
Pain not reproducible by palpation	1
CVD risk factor*	2
Duration of pain 1–60 min	1
Substernal location of pain	2
Marburg Heart Score15–17
Known clinical vascular disease†	1	Score ranges from 0 to 5 points 0–2 points: negative result 3–5 points: positive result
Age/sex (F ≥65 years or M ≥55 years)	1
Increased pain with exercise	1
Pain not reproducible by palpation	1
Patient assumes pain is of cardiac origin	1
INTERCHEST14
History of CAD	1	Score ranges from −1 to +5 points <2 points: CAD negative 2–5 points: CAD positive
Age/sex (F ≥65 years or M ≥55 years)	1
Increased pain with exercise	1
Pain reproducible by palpation	-1
Physician assumes cardiac origin	1
Pain feels like ‘pressure’	1
Acute coronary syndrome
Grijseels rule12 13
History of CAD		Variables present	Normal ECG	Possible/minor MI on ECG	Major MI on ECG
Male sex		0	Home	Possible referral	Always referral and start treating as ACS
Presence of radiation of pain		1	Home	Referral
Presence of nausea/sweating		2	Possible referral	Referral
Abnormal ECG		>=3	Referral	Referral
Bruins Slot rule11
History of CAD	2	Score ranges from 0 to 20 points Cut-off values for low-risk, intermediate-risk and high-risk groups were not reported
Male sex	5
Presence of radiation of pain	8
Presence of nausea/sweating	5

*Family history of CVD, diabetes mellitus, (treated) hypertension, (treated) hyperlipidaemia, smoking or obesity (body mass index ≥30).
†CAD, occlusive vascular disease or cerebrovascular disease.
CAD, coronary artery disease; CVD, cardiovascular disease; MI, myocardial infarction.