Table 2

Components of the clinical decision rules

Coronary artery disease
Gencer rule7
 History of CVD2Score ranges from 0 to 11 points
0–4 points: low risk
5–7 points: moderate risk
8–11 points: high risk
 Age/sex (F ≥65 years or M ≥55 years)2
 Increased pain with exercise1
 Pain not reproducible by palpation1
 CVD risk factor*2
 Duration of pain 1–60 min1
 Substernal location of pain2
Marburg Heart Score15–17
 Known clinical vascular disease†1Score ranges from 0 to 5 points
0–2 points: negative result
3–5 points: positive result
 Age/sex (F ≥65 years or M ≥55 years)1
 Increased pain with exercise1
 Pain not reproducible by palpation1
 Patient assumes pain is of cardiac origin1
 History of CAD1Score ranges from −1 to +5 points
<2 points: CAD negative
2–5 points: CAD positive
 Age/sex (F ≥65 years or M ≥55 years)1
 Increased pain with exercise1
 Pain reproducible by palpation-1
 Physician assumes cardiac origin1
 Pain feels like ‘pressure’1
Acute coronary syndrome
 Grijseels rule12 13
 History of CADVariables presentNormal ECGPossible/minor MI on ECGMajor MI on ECG
 Male sex0HomePossible referralAlways referral and start treating as ACS
 Presence of radiation of pain1HomeReferral
 Presence of nausea/sweating2Possible referralReferral
 Abnormal ECG>=3ReferralReferral
Bruins Slot rule11
 History of CAD2Score ranges from 0 to 20 points
Cut-off values for low-risk, intermediate-risk and high-risk groups were not reported
 Male sex5
 Presence of radiation of pain8
 Presence of nausea/sweating5
  • *Family history of CVD, diabetes mellitus, (treated) hypertension, (treated) hyperlipidaemia, smoking or obesity (body mass index ≥30).

  • †CAD, occlusive vascular disease or cerebrovascular disease.

  • CAD, coronary artery disease; CVD, cardiovascular disease; MI, myocardial infarction.