Algorithm for selective reporting of AST for urine cultures positive for Escherichia coli in adult women
| Resistance profile | Situation 1 | Situation 2 | Situation 3 | Situation 4 |
| AMX S | AMX R/I and (AMC S or TMP-SMX S) | AMX I/R and AMC I/R and TMP-SMX I/R and 3GCs S | 3GCs R | |
| Antibiotics reported on AST | AMX Pivmecillinam* Nitrofurantoin* Fosfomycin* TMP-SMX | AMX Pivmecillinam* Nitrofurantoin* Fosfomycin* TMP-SMX AMC | AMX Pivmecillinam* Nitrofurantoin* Fosfomycin* TMP-SMX AMC Cefixime Ciprofloxacin Levofloxacin Ofloxacin | All antibiotics usually reported on a complete AST |
| Antibiotics occasionally reported on AST | FQ reported only if R/I | FQ reported only if R/I | – | – |
| Antibiotics not reported on AST | FQ not reported if S, 3GCs, AMC | FQ not reported if S, 3GCs | – | – |
Complete AST is available at the prescriber’s request.
When a urine culture is positive, only clinical symptoms can differentiate between asymptomatic bacteriuria and a urinary tract infection; therefore, an antibiotic treatment is not needed for all positive urine cultures.
For more information regarding national guidelines: https://antibioclic.com.
*Do not use for pyelonephritis (lack of diffusion in renal parenchyma).
AMX, amoxicillin; AMC, amoxicillin-clavulanate; AST, antibiotic susceptibility test; FQ, fluoroquinolones; I, intermediate; R, resistant; S, susceptible; TMP-SMX, cotrimoxazole; 3CGs, third-generation cephalosporins.