Table 2

Risk of serious maternal postpartum infections associated with biologics exposure during pregnancy

Maternal serious infections
ParameterOR (95% CI)
UnadjustedBiologics0.90 (0.28 to 2.84)
Model 1Biologics0.88 (0.27 to 2.82)
DMARDs/
immunosuppressants
0.98 (0.68 to 1.40)
Glucocorticoids1.07 (0.64 to 1.77)
Model 2Biologics0.79 (0.24 to 2.54)
DMARDs/
immunosuppressants
0.98 (0.68 to 1.40)
Glucocorticoids1.00 (0.60 to 1.67)
Multiparity0.60 (0.47 to 0.76)
Anxiety1.36 (1.02 to 1.82)
Prior hospital admissions1.19 (1.06 to 1.34)
BMI at baseline1.02 (1.00 to 1.05)
Caesarean section
delivery
2.01 (1.58 to 2.55)
Model 3
HDPS-matched cohort
Biologics1.16 (0.34 to 4.14)
  • BMI, body mass index; DMARDs, disease-modifying antirheumatic drugs; HDPS, high-dimensional propensity score.