Search terms (provisional)
| Concept | Search Terms |
| Chronic obstructive pulmonary disease |
MeSH terms: exp Pulmonary Disease, Chronic Obstructive/ Free text terms: COPD, chronic obstructive pulmonary disease |
| LABA | Free text terms: arformoterol, formoterol, indacaterol, olodaterol, salmeterol, foradi, vilanterol, onbrez, oxis, salmeterol, tulobuterol, vilanterol, bambuterol, bambec, atimos modulate, striverdi respimat, serevent, relvar ellipta |
| LAMA | Free text terms: aclidinium bromide, glycopyrronium bromide, tiotropium, umeclidinium, anoro ellipta, eklira, seebri, Spiriva, incruse, antimuscarinic bronchodilators, glycopyrrolate |
| ICS | Free text terms: beclomethasone, budesonide, fluticasone furoate, fluticasone propionate, fluticasone, mometasone furoate, alvesco, betamethasone, ciclesonide, flixotide, pulmicort, becloforte, becotide, relvar ellipta |
| Exacerbation |
MeSH terms: exp respiratory tract infections/ Free text terms: exacerbation, AECOPD, lower respiratory tract infection, LRTI |
| FEV1 | Forced expiratory volume in 1 s (FEV1) |
| Mortality |
MeSH terms: exp Mortality/exp death/ Free text terms: mortality, death |
| Quality of life |
MeSH terms: exp quality of life/ Free text terms: quality of life, St Georges Respiratory Questionnaire (SGRQ), COPD Assessment Test (CAT) |
| Myocardial Infarction |
MeSH terms: exp myocardial infarction/ Free text terms: myocardial infarction (MI) |
| Stroke |
MeSH terms: exp stroke/ Free text terms: stroke |
| Arrhythmias |
MeSH terms: exp arrhythmias, cardiac/exp atrial fibrillation/ Free text terms: arrhythmia, atrial fibrillation |
| Angina |
MeSH terms: exp angina, unstable/exp angina pectoris Free text terms: unstable angina, angina pectoris |
| Pneumonia |
MeSH terms: exp pneumonia/ Free text terms: pneumonia |
| Type-2 Diabetes |
MeSH terms: exp diabetes mellitus, type 2/ Free text terms: type 2 diabetes (T2DM) |
| Fractures |
MeSH terms: exp osteoporotic fractures/exp fractures, bone Free text terms: osteoporotic fractures, bone fractures |
ICS, inhaled corticosteroids; LABA, long-acting beta-adrenoceptor agonist; LAMA, long-acting muscarinic antagonists.