Number of events and event rates during follow-up
| Outcome | GBP (n=5321) | Control (n=5321) | HR (95% CI) | P value |
| All-cause mortality | 183 (72.90) | 351 (142.06) | 0.51 (0.43 to 0.62) | <0.0001 |
| Cardiovascular | ||||
| Cardiovascular disease | 108 (43.54) | 150 (61.54) | 0.66 (0.51 to 0.85) | 0.0014 |
| Fatal cardiovascular disease | 21 (8.38) | 64 (25.94) | 0.34 (0.20 to 0.56) | <0.0001 |
| Acute myocardial infarction | 51 (20.43) | 85 (34.69) | 0.55 (0.39 to 0.79) | 0.0010 |
| Coronary heart disease | 309 (128.66) | 274 (114.28) | 1.13 (0.95 to 1.34) | 0.156 |
| Fatal coronary heart disease | 28 (11.17) | 77 (31.20) | 0.35 (0.22 to 0.54) | <0.0001 |
| Congestive heart failure | 109 (43.94) | 225 (93.05) | 0.49 (0.39 to 0.62) | <0.0001 |
| Atrial fibrillation | 204 (83.64) | 213 (88.16) | 0.93 (0.76 to 1.14) | 0.486 |
| Valvular heart disease | 21 (8.39) | 32 (13.00) | 0.64 (0.36 to 1.14) | 0.131 |
| Stroke | 59 (23.69) | 71 (28.94) | 0.77 (0.54 to 1.10) | 0.158 |
| Deep vein thrombosis/pulmonary embolism | 56 (22.48) | 59 (24.07) | 1.01 (0.69 to 1.48) | 0.952 |
| Diabetes related | ||||
| Hypoglycaemia (with or without coma) | 43 (17.24) | 46 (18.72) | 1.04 (0.68 to 1.60) | 0.844 |
| Hyperglycaemia | 23 (9.20) | 89 (36.37) | 0.33 (0.21 to 0.53) | <0.0001 |
| Gastrointestinal | ||||
| Gastrointestinal surgery (not GBP) | 936 (422.59) | 301 (125.76) | 3.33 (2.91 to 3.80) | <0.0001 |
| Abdominal pain | 558 (239.25) | 124 (50.94) | 5.52 (4.51 to 6.75) | <0.0001 |
| Gallstone, gallbladder disease and pancreatitis | 312 (129.31) | 125 (51.30) | 2.49 (2.02 to 3.08) | <0.0001 |
| Gastrointestinal ulcer and reflux | 239 (98.58) | 46 (18.73) | 5.42 (3.91 to 7.51) | <0.0001 |
| Hernia | 235 (97.00) | 86 (35.17) | 2.75 (2.14 to 3.54) | <0.0001 |
| Bowel obstruction | 232 (95.29) | 27 (10.97) | 9.47 (6.31 to 14.20) | <0.0001 |
| Gastrointestinal leakage | 40 (16.05) | 7 (2.84) | 5.54 (2.46 to 12.45) | <0.0001 |
| Liver disease | 30 (12.00) | 40 (16.26) | 0.73 (0.45 to 1.19) | 0.205 |
| Surgical | ||||
| Plastic surgery | 380 (158.08) | 22 (8.94) | 19.85 (12.86 to 30.67) | <0.0001 |
| Wound complications | 290 (120.87) | 87 (35.55) | 3.45 (2.70 to 4.42) | <0.0001 |
| Bleeding | 172 (70.50) | 26 (10.57) | 6.87 (4.49 to 10.52) | <0.0001 |
| Other | ||||
| Psychiatric disorder | 317 (131.64) | 268 (111.93) | 1.33 (1.13 to 1.58) | 0.0008 |
| Alcohol abuse | 180 (73.10) | 65 (26.52) | 2.90 (2.16 to 3.88) | <0.0001 |
| Cancer | 153 (61.80) | 188 (77.41) | 0.78 (0.63 to 0.97) | 0.0257 |
| Malnutrition | 128 (51.69) | 46 (18.72) | 2.81 (1.98 to 3.97) | <0.0001 |
| Kidney disease | 105 (42.38) | 187 (76.87) | 0.58 (0.45 to 0.75) | <0.0001 |
| Pulmonary complications | 86 (34.66) | 114 (46.64) | 0.84 (0.63 to 1.13) | 0.249 |
| Anaemia | 84 (33.78) | 46 (18.71) | 1.92 (1.33 to 2.76) | 0.0005 |
| Amputation | 15 (5.99) | 23 (9.33) | 0.51 (0.26 to 0.98) | 0.0432 |
| Dementia | 4 (1.60) | 12 (4.87) | 0.46 (0.14 to 1.57) | 0.214 |
Event rates (%) per 10 000 person-years.
GBP, gastric bypass.