Number of cases | Surgery (%) | P value* | Unadjusted ORs | Adjusted ORs† |
Mann-Whitney U test or χ2 test | (95% CIs) | (95% CIs) | ||
All (n=1596) | 86.8 | – | – | – |
Age at diagnosis (years): | ||||
<40 (n=103) | 96.1 | <0.001 | 1.00 | 1.00 |
40–49 (n=210) | 94.3 | 0.67 (0.18 to 2.30) | 0.74 (0.17 to 3.17) | |
50–59 (n=354) | 92.7 | 0.51 (0.15 to 1.59) | 0.80 (0.21 to 3.06) | |
60–69 (n=438) | 89.9 | 0.36 (0.11 to 1.08) | 0.59 (0.16 to 2.14) | |
70–79 (n=324) | 80.9 | 0.17 (0.05 to 0.51) | 0.35 (0.10 to 1.27) | |
80+ (n=167) | 62.3 | 0.07 (0.02 to 0.20) | 0.17 (0.04 to 0.65) | |
FIGO stage: | ||||
IA (n=212) | 98.1 | <0.001 (excluding UK) | 1.00 | 1.00 |
IB/C (n=131) | 96.2 | 0.48 (0.11 to 2.12) | 0.57 (0.12 to 2.73) | |
IIA (n=23) | 95.7 | 0.42 (0.04 to 10.39) | 0.47 (0.04 to 5.86) | |
IIB/C (n=123) | 96.2 | 0.57 (0.13 to 2.49) | 0.72 (0.15 to 3.44) | |
IIIA (n=320) | 90.3 | 0.18 (0.05 to 0.54) | 0.42 (0.11 to 1.52) | |
IIIB/C (n=376) | 93.4 | 0.27 (0.08 to 0.83) | 0.48 (0.13 to 1.78) | |
IV (n=320) | 70.6 | 0.05 (0.01 to 0.13) | 0.13 (0.04 to 0.45) | |
Unknown (n=91) | (43.9) | - | - | |
Differentiation: | ||||
Well (n=148) | 98.0 | 0.021 (excluding UK) | 1.00 | 1.00 |
Moderate (n=311) | 90.4 | 0.19 (0.05 to 0.68) | 0.33 (0.09 to 1.23) | |
Poorly/undifferentiated (n=841) | 89.8 | 0.18 (0.05 to 0.60) | 0.39 (0.11 to 1.38) | |
Unknown (n=296) | (68.8) | - | - | |
Histology: | ||||
Serous adenocarcinoma (n=789) | 92.1 | 0.002 (excluding UK) | 1.00 | 1.00 |
Mucinous adenocarcinoma (n=144) | 89.6 | 0.73 (0.39 to 1.39) | 0.88 (0.34 to 2.34) | |
Endometrioid adenocarcinoma (n=157) | 98.7 | 6.61 (1.57 to 39.48) | 1.07 (0.41 to 2.85) | |
Clear cell adenocarcinoma (n=87) | 95.4 | 1.77 (0.60 to 5.87) | 0.90 (0.25 to 3.21) | |
Adenocarcinoma (NOS) (n=417) | 69.3 | 0.19 (0.14 to 0.27) | 0.28 (0.17 to 0.45) | |
Unknown (n=2) | (100) | - | - | |
Socioeconomic (SEIFA): | ||||
Low (n=495) | 84.9 | 0.058 | 1.00 | 1.00 |
Low/med (n=398) | 86.9 | 1.19 (0.80 to 1.77) | 0.81 (0.46 to 1.43) | |
Med/high (n=315) | 86.0 | 1.10 (0.72 to 1.68) | 1.00 (0.52 to 1.93) | |
High (n=388) | 89.7 | 1.55 (1.01 to 2.39) | 1.19 (0.63 to 2.25) | |
Geographic remoteness: | ||||
Low (n=1326) | 87.0 | 0.507 | 1.00 | 1.00 |
Moderate (n=128) | 85.9 | 0.91 (0.53 to 1.59) | 0.75 (0.35 to 1.58) | |
High (n=142) | 85.2 | 0.86 (0.51 to 1.45) | 0.49 (0.24 to 0.99) | |
Diagnostic period (calendar years) | ||||
1984–1989 (n=285) | 85.7 | 0.986 | 1.00 | 1.00 |
1990–1999 (n=596) | 87.6 | 1.19 (0.77 to 1.82) | 1.03 (0.56 to 1.89) | |
2000–2009 (n=461) | 87.2 | 1.14 (0.73 to 1.80) | 1.19 (0.60 to 2.37) | |
2010–2015 (n=254) | 85.4 | 0.99 (0.59 to 1.64) | 0.84 (0.37 to 1.91) |
*Pearson’s χ2 (likelihood ratio), Mann-Whitney U test (see ‘Methods’ section).
†Derived from multiple logistic regression, adjusting for the other variables in the table.
FIGO, International Federation of Gynecology and Obstetrics; NOS, not otherwise specified; SEIFA, Socio-Economic Indexes for Areas; UK, Unknown.