Table 2

Randomised controlled tiral (RCT) detail

Studies
Number of RCTs127/147 (86.4)
Number of pilot studies13/147 (8.8)
Number of RCT protocols7/147 (4.8)
World region for recruitment
  Asia54/147 (36.7)
  North America36/147 (24.5)
 Europe26/147 (17.7)
 Africa15/147 (8.5)
 Latin America1/147 (0.7)
 Australasia15/147 (8.5)
Year published
 201226/147 (17.8)
 201324/147 (16.3)
 201424/147 (16.3)
 201533/147 (22.4)
 201640/147 (27.2)
Number of sites
 1132/147 (89.8)
 2–39/147 (6.1)
 4–52/147 (1.4)
 >54/147 (2.7)
Number of participants in full RCTs
 <104/127 (3.1)
 11–5062/127 (48.8)
 51–10039/127 (30.7)
 101–15011/127 (8.7)
 >15011/127 (8.7)
Participants recruited
 <18 years24/147 (16.3)
 >18 years59/147 (40.1)
 Mixed age range25/147 (17.0)
 Not stated34/147 (23.1)
 N/A (protocol)‡ 5/147 (3.4)
Type of intervention
 Dressings and wound care38/147 (25.9)
 Surgical technique19/147 (12.9)
 Treatment of pain or itch*16/147 (10.9)
 Impact of exercise and rehabilitation13/147 (8.8)
 Intensive care management10/147 (6.8)
 Treatment of hypermetabolism8/147 (5.4)
 Nutrition8/147 (5.4)
 Scar management7/147 (4.8)
 Treatment of inhalational injury3/147 (2.0)
 Use of topical rHGM3/147 (2.0)
 Use of rHGH3/147 (2.0)
 Sugar management2/148 (2.0)
 Treatment of infection2/147 (1.4)
 Treatment of DVT2/147 (1.4)
 Blood management2/147 (1.4)
 Extracorporeal shock wave therapy2/147 (1.4)
 Platelet-rich plasma use2/147 (1.4)
 Others†7/147 (5.4)
  • *Inc. distraction for dressing changes.

  • †Inc. levamisole, hyperbaric oxygen, fibroblast growth factor, oral calcium use, ketoconazole, low intensity laser.

  • ‡No participants reported as study is a protocol.

  • DVT, deep vein thrombosis; N/A, not applicable; rHGH, recombinant human growth hormone; rHGM, recombinant Human Granulocyte-Macrophage colony-stimulating factor.