Characteristics of participants in the MHOO and MUOO phenotypes according to the sleep duration categories
| Characteristics | MHOO | P value | MUOO | P value | P(MHOO vs MAOO) | ||||
| 5 to 6 | 7 to 8 | 9 to 10 | 5 to 6 | 7 to 8 | 9 to 10 | ||||
| n=174 | n=1345 | n=413 | n=271 | n=1477 | n=469 | ||||
| Age, years | 56.2±1.1 | 48.6±0.4 | 48±0.7 | <0.001 | 58.3±0.8 | 53±0.3 | 56±0.6 | <0.001 | <0.001 |
| Men, % | 44.8 | 45.6 | 47.5 | 0.763 | 42.8 | 48.9 | 48.4 | 0.181 | 0.171 |
| Smoking status, % | 0.057 | 0.392 | 0.038 | ||||||
| Never | 66.7 | 72.4 | 71.7 | 69.3 | 67.9 | 68 | |||
| Former | 3.4 | 4.1 | 1.7 | 5.6 | 3.5 | 4.7 | |||
| Currently | 29.9 | 23.5 | 26.6 | 25.2 | 28.6 | 27.3 | |||
| Alcohol consumption, % | |||||||||
| Diabetes, % | 1.1 | 0.6 | 0.7 | 0.481 | 11.4 | 6.3 | 8.1 | 0.009 | <0.001 |
| Hypertension, % | 16.2 | 6.5 | 8.2 | <0.001 | 39.1 | 22.4 | 30.6 | <0.005 | <0.001 |
| BMI, kg/m2 | 25.6±0.2 | 25.5±0.1 | 25.3±0.1 | 0.08 | 26.3±0.2 | 26.5±0.1 | 26.4±0.1 | 0.431 | <0.001 |
| WC, cm | 88.2±0.6 | 86.9±0.2 | 86.3±0.4 | 0.025 | 90.5±0.5 | 90.6±0.2 | 90.9±0.4 | 0.83 | <0.001 |
| SBP, mm Hg | 127±1.5 | 122±0.4 | 121±0.9 | <0.001 | 138±1.1 | 134±0.5 | 136±0.9 | 0.004 | <0.001 |
| DBP, mm Hg | 81±0.8 | 80±0.3 | 79±0.5 | 0.064 | 87±0.7 | 87±0.3 | 86±0.5 | 0.303 | <0.001 |
| FPG, mg/dL | 92.8±1.6 | 89.9±0.4 | 89.5±0.7 | 0.033 | 111.1±2.1 | 111.2±1 | 109±1.6 | 0.494 | <0.001 |
| HOMA-IR | 3.6±0.6 | 2.8±0.1 | 3.0±0.2 | 0.012 | 4.8±0.3 | 5.9±0.3 | 5.8±0.5 | 0.223 | <0.001 |
| Uric acid, mg/dL | 5.0±0.1 | 4.9±0.04 | 4.9±0.07 | 0.738 | 6.1±0.1 | 5.9±0.1 | 5.9±0.1 | 0.593 | <0.001 |
| hs-CRP, mg/dL | 2.24±0.31 | 2.12±0.13 | 2.34±0.21 | 0.69 | 3.03±0.23 | 3.2±0.17 | 3.34±0.32 | 0.816 | <0.001 |
| TC, mg/dL | 195.1±2.7 | 187.9±1.0 | 186.9±1.7 | 0.025 | 206.5±2.5 | 199.5±1.1 | 197.8±2 | 0.017 | <0.001 |
| TGs, mg/dL | 109.1±4.1 | 110±1.7 | 108.6±2.6 | 0.912 | 239.2±9.9 | 237.7±4.6 | 227.6±7.9 | 0.52 | <0.001 |
| HDL-C, mg/dL | 59.8±1.1 | 57.2±0.4 | 56.3±0.8 | 0.053 | 48.1±0.8 | 47.6±0.6 | 47.2±0.6 | 0.86 | <0.001 |
| LDL-C, mg/dL | 126.3±2.5 | 120.1±0.9 | 119.6±1.6 | 0.054 | 125.9±2.5 | 119.3±1.1 | 119.8±2.2 | 0.067 | 0.761 |
| ApoA1, g/L | 1.2±0.02 | 1.16±0.01 | 1.14±0.01 | 0.299 | 1.15±0.02 | 1.09±0.01 | 1.08±0.01 | 0.093 | <0.001 |
| ApoB, g/L | 0.97±0.02 | 0.91±0.01 | 0.89±0.01 | <0.001 | 1.1±0.02 | 1.02±0.01 | 1.01±0.01 | <0.001 | <0.001 |
| ApoB/A1 | 0.86±0.02 | 0.83±0.01 | 0.81±0.01 | 0.093 | 1.01±0.02 | 1±0.01 | 0.99±0.02 | 0.734 | <0.001 |
Data are presented as the mean±SE or proportion (%)±SE. P values represent the difference across sleep duration categories. P (MHOO vs MUOO) represents the difference in the overall value for each variable between MHOO and MUOO individuals.
ApoB, apolipoprotein B; ApoB/A1, apolipoprotein B/apolipoprotein A1; BMI, body mass index; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homoeostasis model assessment of insulin resistance; hs-CRP, high-sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol MHOO, metabolically healthy overweight/obese; MUOO, metabolically unhealthy overweight/obese; SBP/DBP, systolic/diastolic blood pressure; TC, total cholesterol; WC, waist circumference.