Table 1

Patients’ characteristics during pregnancy

VariablesTotal
n=338(%)
Live birth
n=300 (%)
Fetal loss
n=38 (%)
P value
Characteristics
 Age (year, mean±SD)29.5±4.029.7±3.928.6±4.50.131
 History of SLE (year, mean±SD)5.7±4.35.8±4.44.5±4.10.091
 History of therapeutic abortion
 (frequency, mean±SD, range)
0.04±0.2
(0–2)
0.04±0.2
(0–1)
0.08±0.4
(0–2)
0.657
 History of spontaneous abortion (frequency, mean±SD, range)0.4±0.9
(0–7)
0.4±1.0
(0–7)
0.3±0.6
(0–7)
0.687
 Region
  City237 (70.1)210 (70.0)27 (71.1)0.894
  Rural101 (29.9)90 (30.0)11 (28.9)
 Nullipara291 (86.1)258 (86.0)33 (86.8)0.888
 Pre-pregnancy hypertension10 (3.0)6 (2.0)4 (10.5)0.016*
 Unplanned pregnancy45 (13.3)32 (10.7)13 (34.2)<0.001*
SLE clinical features
 Renal disorder97 (28.7)76 (25.3)21 (55.3)<0.001*
 Mucocutaneous106 (31.4)94 (31.3)12 (31.6)0.975
 Haematological disorder66 (19.5)53 (17.7)13 (34.2)0.015*
 Neurological disorder5 (1.5)3 (1.0)2 (5.3)0.181
 Arthritis70 (20.7)63 (21.0)7 (18.4)0.712
 Serositis17 (5.0)10 (3.3)7 (18.4)0.001*
Laboratory features during pregnancy
 24 hour-urinary protein (g, mean±SD)1.04±2.430.6±1.54.3±4.9<0.001*
 Anti-dsDNA261 (77.2)226 (75.3)35 (92.1)0.020*
 Anti-Ro/SSA150 (44.4)132 (44.0)18 (47.4)0.694
 Anti-La/SSB47 (13.9)41 (13.7)6 (15.8)0.722
 Anti-Sm20 (5.9)16 (5.3)4 (10.5)0.361
 aPL46 (13.6)38 (12.7)8 (21.1)0.156
 hypocomplementemia-C3 90 (26.6)62 (20.7)28 (73.7)<0.001*
 hypocomplementemia-C4 60 (17.8)45 (15.0)15 (39.5)<0.001*
  • *P<0.05.

  • SLE, systemic lupus erythematosus.