Multivariable analysis of fetal loss
| Variables | Risk factors included individually | Risk factors included simultaneously | Risk F actors selected using stepwise regression |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Unplanned pregnancy | 4.33 (1.71 to 11.00)** | 3.01 (0.90 to 10.02) | 2.84 (1.12 to 7.22)* |
| Pre-pregnancy hypertension | 6.45 (1.60 to 26.06)** | 5.24 (0.74 to 37.38) | – |
| hypocomplementemia-C3 | 11.43 (5.15 to 25.33)** | 7.09 (2.60 to 19.36)** | 5.46 (2.30 to 12.97)** |
| hypocomplementemia-C4 | 3.80 (1.81 to 7.98)** | 0.56 (0.19 to 1.60) | – |
| Renal disorder | 3.58 (1.76 to 7.28)** | 0.33 (0.09 to 1.15) | – |
| Haematological disorder | 2.19 (1.02 to 4.69)* | 0.90 (0.32 to 2.53) | – |
| Anti-dsDNA | 3.62 (1.07 to 12.17)* | 2.58 (0.65 to 10.24) | – |
| 24 hour-urinary protein | |||
| Urinary protein<0.3 g/24 hours | 1 | 1 | 1 |
| 0.3≤urinary protein<1.0 g/24 hours | 3.34 (1.05 to 10.68)* | 3.23 (0.90 to 11.65) | 2.10 (0.63 to 6.95) |
| Urinary protein≥1.0 g/24 hours | 14.85 (6.25 to 35.31)** | 16.20 (3.90 to 67.29)** | 5.89 (2.30 to 15.06)** |
*P<0.05; **P<0.01; Multivariable models adjusted for age at conception (continuous), history of SLE (continuous), history of therapeutic abortion (continuous), history of spontaneous abortion (continuous), region (city vs rural), nullipara (nullipara vs multipara).
SLE, systemic lupus erythematosus .