Table 2

Multivariable analysis of fetal loss

VariablesRisk factors included individuallyRisk factors included simultaneouslyRisk F actors selected using stepwise regression
OR (95% CI)OR (95% CI)OR (95% CI)
Unplanned pregnancy4.33 (1.71 to 11.00)**3.01 (0.90 to 10.02)2.84 (1.12 to 7.22)*
Pre-pregnancy hypertension6.45 (1.60 to 26.06)**5.24 (0.74 to 37.38)
hypocomplementemia-C3 11.43 (5.15 to 25.33)**7.09 (2.60 to 19.36)**5.46 (2.30 to 12.97)**
hypocomplementemia-C4 3.80 (1.81 to 7.98)**0.56 (0.19 to 1.60)
Renal disorder3.58 (1.76 to 7.28)**0.33 (0.09 to 1.15)
Haematological disorder2.19 (1.02 to 4.69)*0.90 (0.32 to 2.53)
Anti-dsDNA3.62 (1.07 to 12.17)*2.58 (0.65 to 10.24)
24 hour-urinary protein
 Urinary protein<0.3 g/24 hours111
 0.3≤urinary protein<1.0 g/24 hours3.34 (1.05 to 10.68)*3.23 (0.90 to 11.65)2.10 (0.63 to 6.95)
 Urinary protein≥1.0 g/24 hours14.85 (6.25 to 35.31)**16.20 (3.90 to 67.29)**5.89 (2.30 to 15.06)**
  • *P<0.05; **P<0.01; Multivariable models adjusted for age at conception (continuous), history of SLE (continuous), history of therapeutic abortion (continuous), history of spontaneous abortion (continuous), region (city vs rural), nullipara (nullipara vs multipara).

  • SLE,  systemic lupus erythematosus .