Table 2

ORs for prescribing high-cost drugs by dispensing practice status for each class of drug

ComparisonUnivariable OR (95% CI)Adjusted OR (95% CI)*Mean % high cost in dispensing practicesMean % high cost in non-dispensing practicesMean cost per dose in pence, dispensing practices (95% CI)Mean cost per dose in pence, non-dispensing practices (95% CI)Total no of prescriptions (items) in England during study month
Statins1.66 (1.64 to 1.68)1.51 (1.49 to 1.53)4.742.787.44 (7.27 to 7.62)6.27 (6.23 to 6.31)5 434 443
PPI1.14 (1.12 to 1.17)1.11 (1.09 to 1.13)1.611.465.57 (5.53 to 5.62)5.46 (5.44 to 5.49)4 517 467
ACEi2.42 (2.32 to 2.52)2.58 (2.46 to 2.70)0.660.234.30 (4.22 to 4.38)4.24 (4.23 to 4.25)3 601 634
ARB4.79 (4.72 to 4.87)5.11 (5.02 to 5.20)10.792.8411.09 (10.72 to 11.47)8.19 (8.13 to 8.24)1 507 419
  • *Adjusted for IMD, practice list size and number of GPs.

  • ACEi, ACE inhibitor; ARB, angiotensin receptor blocker; IMD, Index of Multiple Deprivation; PPI, proton pump inhibitor.