Table 3

Time to response (days)

	Time to response		Adjusted HR (95% CI)	P value
	Mean [SD]	Median [25th, 75th centile]	Adjusted HR (95% CI)	P value
Short message and protocol	51.6 [64.7]	28 [1, 77]	0.91 (0.55 to 1.51)	0.72
Long message	60 [65.3]	42 [1, 77]	0.91 (0.55 to 1.51)	0.72

Adjusted for year of publication, size of trial and if the author had multiple trials included. Total N included=88.