Table 4

Predictors of SSI

Univariate logistic regression
Type of risk factorVariableOR (95% CI)P value
Non-modifiable prior to surgeryBMI (per kg/m2)1.09 (1.04 to 1.13)<0.001
Age (per year)1.01 (0.99 to 1.04)0.236
ASA three or more (vs less than three or missing)1.73 (0.93 to 3.22)0.083
Albumin (per g/L)0.98 (0.93 to 1.02)0.309
FIGO stage (per unit)1.05 (0.76 to 1.45)0.773
Diabetic requiring insulin (vs not requiring insulin for glycaemic control)5.00 (1.61 to 15.5)0.005
Neoadjuvant chemotherapy (vs none)0.50 (0.22 to 1.17)0.110
Cancer type
 Endometrium (vs ovarian)1.48 (0.72 to 3.04)0.291
 Benign (vs ovarian)0.68 (0.08 to 5.64)0.722
 Cervical (vs ovarian)0.87 (0.36 to 2.10)0.752
 Other (vs ovarian)0.73 (0.16 to 3.34)0.682
Non-modifiable surgical risk factorSurgical radicality score (per unit)1.02 (0.89 to 1.19)0.718
Clean contaminated (vs clean)2.26 (0.67 to 7.66)0.189
Incision site
 Above umbilicus (vs transverse)1.64 (0.36 to 7.39)0.519
 Below umbilicus (vs transverse)2.15 (0.46 to 10.19)0.333
Modifiable at time of surgeryChlorhexadine skin preparation (vs betadine)0.54 (0.30 to 0.97)0.039
Wound drain (vs none)3.23 (1.68 to 6.19)<0.001
Subcutaneous fat stitch (vs none)1.50 (0.76 to 2.95)0.245
Staples (vs subcuticular suture)3.58 (1.84 to 6.97)<0.001
Prophylactic postoperative antibiotics (vs none/missing)1.69 (0.86 to 3.31)0.126
Multivariate logistic regression
Non-modifiable prior to surgeryBMI (per kg/m2)1.08 (1.03 to 1.14)0.001
ASA (per unit)1.01 (0.48 to 2.11)0.989
Diabetic requiring insulin (vs not requiring insulin for glycaemic control)3.34 (0.90 to 12.39)0.071
Modifiable at time of surgeryChlorhexadine (vs betadine)0.58 (0.30 to 1.134)0.109
Drain (vs none)2.92 (1.41 to 6.04)0.004
Staples (vs subcuticular suture)3.13 (1.50 to 6.56)0.002
  • ASA, American Society of Anesthesiologists; BMI, body mass index; SSI, surgical site infection.