Non-motor symptoms subjective questionnaires
| FMD patients vs controls | RLS+ vs RLS− FMD patients | |||||
| FMD patients | Controls | P value | FMD/RLS+ | FMD/RLS− | P value | |
| BDI-II (depression) | ||||||
| Total (N) | 91 | 76 | 39 | 52 | ||
| ≥14 | 53.9% | 10.5% | <0.0001* | (64.1%) | (46.1%) | 0.044 |
| Mean score (SD) | 18.3 (14) | 6.0 (6) | <0.00001* | 22.1 (14) | 15.8 (13) | 0.047 |
| STAI-X2 (anxiety trait) | ||||||
| Total (N) | 90 | 76 | 40 | 50 | ||
| Mean score (SD) | 47.0 (12) | 37.8 (10) | <0.00001* | 49.8 (12) | 44.7 (12) | 0.044 |
| FSS (fatigue) | ||||||
| Total (N) | 90 | 76 | 38 | 52 | ||
| Mean score (SD) | 5.5 (1) | 3.0 (1) | <0.00001* | 5.8 (1) | 5.2 (2) | 0.17 |
| ESS (daytime sleepiness) | ||||||
| Total (N) | 88 | 76 | 37 | 51 | ||
| Mean score (SD) | 10.6 (5) | 6.5 (4) | <0.00001* | 11.8 (5) | 9.7 (5) | 0.07 |
All intergroup comparisons were performed using Mann-Whitney U test for quantitative parameters and χ2 for qualitative ones, p values shown are nominal uncorrected results.
*Significant results after correction for multiple testing for four comparisons (p<0.05).
BDI-II, Beck Depression Inventory II; ESS, Epworth Sleepiness Scale; FMD, functional movement disorder; FSS, Fatigue Severity Scale; RLS, restless legs syndrome; STAI-X2, State/Trait Anxiety Inventory X2.