Timepoint | Enrolment | Allocation | Post-randomisation | ||||
Before surgery | 0 | Intra-operative | 4 hours post surgery | 24 hours | 30 days | 180 days | |
Enrolment | |||||||
Eligibility screen | X | ||||||
Informed consent | X | ||||||
Allocation | X | ||||||
Interventions | |||||||
Cardiac output-guided haemodynamic therapy | |||||||
Usual care | |||||||
Assessments | |||||||
Demographic information | X | ||||||
Medical history | X | ||||||
EuroQol 5-dimension, 3-level (UK only) | X | X | X | ||||
Intraoperative information | X | X | |||||
Fluids and inotropic therapy | X | X | |||||
Acute cardiac event | X | X | |||||
Postoperative infection | X | ||||||
Acute kidney injury | X | ||||||
Other postoperative morbidity | X | ||||||
Mortality | X | ||||||
End-of-trial form | X |