Study population descriptive characteristics at baseline (T0)
| Patient characteristic | All patients | Patients with ≥10 prescribed medication classes | Patients with ≥3 chronic diseases | ||||
| n (%)* | Yes n (%)* | No n (%)* | P value† | Yes n (%)* | No n (%)* | P value† | |
| N | 726 (100%) | 89 (12.3%) | 637 (87.7%) | 223 (30.7%) | 503 (69.3%) | ||
| Median age (IQR), years | 76.4 (72.9–80.3) | 78.8 (73.8–83.2) | 76.1 (72.9–79.8) | 0.013 | 77.6 (74.1–81.1) | 76.0 (72.8–79.8) | 0.002 |
| Mean deprivation score (SD) | 1.4 (2.6) | 1.8 (2.3) | 1.4 (2.6) | 0.075 | 1.6 (2.4) | 1.3 (2.6) | 0.272 |
| Gender | |||||||
| Male | 348 (47.9%) | 33 (37.1%) | 315 (49.5%) | 0.038 | 112 (50.2%) | 236 (46.9%) | 0.246 |
| Female | 378 (52.1%) | 56 (62.9%) | 322 (50.6%) | 111 (48.8%) | 267 (53.1%) | ||
| Social class | |||||||
| Unskilled | 161 (22.2%) | 29 (32.6%) | 132 (20.7%) | 0.064 | 55 (24.7%) | 106 (21.1%) | 0.636 |
| Skilled | 565 (77.8%) | 60 (67.4%) | 505 (79.3%) | 168 (75.3%) | 397 (78.9%) | ||
| Education | |||||||
| Basic | 433 (59.6%) | 66 (75%) | 367 (57.9%) | 0.014 | 155 (70.1%) | 278 (55.5%) | 0.006 |
| Higher | 293 (40.4%) | 22 (25.0%) | 267 (42.1%) | 66 (29.9%) | 223 (44.5%) | ||
| Marital status‡ | |||||||
| Married | 342 (47.1%) | 35 (39.3%) | 307 (42.3%) | 0.127 | 94 (42.3%) | 248 (49.3%) | 0.296 |
| Separated/divorced | 34 (4.7%) | 2 (2.3%) | 32 (5.0%) | 12 (5.4%) | 22 (4.4%) | ||
| Widowed | 224 (30.9%) | 39 (43.8%) | 185 (29.1%) | 81 (36.5%) | 143 (28.4%) | ||
| Single/never married | 125 (17.2%) | 13 (14.6%) | 112 (17.6%) | 35 (15.8%) | 90 (17.9%) | ||
| Living arrangement‡ | |||||||
| Husband/wife/life partner | 333 (45.9%) | 33 (37.1%) | 300 (47.2%) | 0.246 | 92 (41.4%) | 241 (47.9%) | 0.508 |
| Family/relatives | 90 (12.4%) | 12 (13.5%) | 78 (12.3%) | 27 (12.2%) | 63 (12.5%) | ||
| Living alone | 266 (36.6%) | 37 (41.6%) | 229 (36.0%) | 91 (41.0%) | 175 (34.8%) | ||
| Other | 36 (5.0%) | 7 (7.9%) | 29 (4.6%) | 12 (5.4%) | 24 (4.8%) | ||
*Unless otherwise stated.
†Cluster adjusted Mann-Whitney test (age), t-test (deprivation score) or χ2 test for categorical variables.
‡Missing for two people.