Article | Risk factor category | Mortality risk factor on admission | Estimate type | Estimate (95% CI) | Adjusted |
Biai et al 21 | No data | ||||
Phiri et al 25 | Age | Age (months) | HR | 0.92 (0.87 to 0.97) | Yes |
Comorbid conditions | HIV positive | HR | 10.49 (4.05 to 27.20) | Yes | |
Bacteraemia | HR | 2.17 (0.84 to 5.64) | Yes | ||
Diagnosis | Malaria (any parasite/mL blood) | HR | 1.25 (0.67 to 2.34) | No | |
Growth parameters | Wasting (<−2 z-score weight-for-height) | HR | 0.74 (0.31 to 1.80) | No | |
Stunting (<−2 z-score height-for-age) | HR | 0.61 (0.30 to 1.22) | No | ||
Labs/Assessments | Iron deficiency (>5.6 sTfR/log ferritin) | HR | 0.91 (0.41 to 2.03) | No | |
Maternal influence | Mother education (some) | HR | 1.63 (0.72 to 3.70) | No | |
Sex | Male | HR | 1.54 (0.68 to 3.52) | Yes | |
Social determinants of health | Rural residency | HR | 1.63 (0.63 to 4.20) | Yes | |
Parents unemployed | HR | 4.15 (1.61 to 10.74) | Yes | ||
Symptoms | Splenomegaly | HR | 0.36 (0.16 to 0.80) | Yes | |
Phiri et al 23 | No data | ||||
Zucker et al 24 | Intervention | PS, quinine, TS treatment x5d (ref: chloroquine or no antimalarial) | RR | 0.33 (0.19 to 0.65) | Unspecified |
Labs/Assessments | Severe anaemia (Hgb<5 g/dL) | RR | 1.52 (1.22 to 1.90) | Unspecified | |
Olupot-Olupot et al 26 | Intervention | 30 mL/kg transfusion vs 20 mL/kg transfusion | RR | 0.18 (0.02 to 1.42) | Unspecified |
Opoka et al 22 | Diagnosis | Severe malarial anaemia* | HR | 16.26 (2.03 to 130.34) | Yes |
Cerebral malaria* | HR | 4.45 (0.51 to 38.55) | Yes |
*Risk factor for readmission.
Hgb, haemoglobin; PDM, postdischarge mortality; RR, relative risk.