Table 8

Risk factors for PDM in anaemia/malaria studies

ArticleRisk factor categoryMortality risk factor on admissionEstimate typeEstimate (95% CI)Adjusted
Biai et al 21 No data
Phiri et al 25 AgeAge (months)HR 0.92 (0.87 to 0.97) Yes
Comorbid conditionsHIV positiveHR 10.49 (4.05 to 27.20) Yes
BacteraemiaHR2.17 (0.84 to 5.64)Yes
DiagnosisMalaria (any parasite/mL blood)HR1.25 (0.67 to 2.34)No
Growth parametersWasting (<−2 z-score weight-for-height)HR0.74 (0.31 to 1.80)No
Stunting (<−2 z-score height-for-age)HR0.61 (0.30 to 1.22)No
Labs/AssessmentsIron deficiency (>5.6 sTfR/log ferritin)HR0.91 (0.41 to 2.03)No
Maternal influenceMother education (some)HR1.63 (0.72 to 3.70)No
SexMaleHR1.54 (0.68 to 3.52)Yes
Social determinants of healthRural residencyHR1.63 (0.63 to 4.20)Yes
Parents unemployedHR 4.15 (1.61 to 10.74) Yes
SymptomsSplenomegalyHR 0.36 (0.16 to 0.80) Yes
Phiri et al 23 No data
Zucker et al 24 InterventionPS, quinine, TS treatment x5d (ref: chloroquine or no antimalarial)RR 0.33 (0.19 to 0.65) Unspecified
Labs/AssessmentsSevere anaemia (Hgb<5 g/dL)RR 1.52 (1.22 to 1.90) Unspecified
Olupot-Olupot et al 26 Intervention30 mL/kg transfusion vs 20 mL/kg transfusionRR0.18 (0.02 to 1.42)Unspecified
Opoka et al 22 DiagnosisSevere malarial anaemia*HR 16.26 (2.03 to 130.34) Yes
Cerebral malaria*HR4.45 (0.51 to 38.55)Yes
  • *Risk factor for readmission.

  • Hgb, haemoglobin; PDM, postdischarge mortality; RR, relative risk.