Table 3

Outcome characteristics

Author IDIntervention/ExposureIPM (%)*Follow-up timesLoss to follow-up (%)*PD rehospitalised (%)*PDM (%)*Place of PD deathPDM statistics†
All admissions/unspecified infectious admissions
 Veirum et al 8 15Days 1, 14, 30, 91, 182, 365877% at home
23% in hospital
63% at 13 w
 Moisi et al 9 1 year17.75.2
 Wiens et al 10 4.92, 4, 6 months1.716.54.967% out of hospital
33% in hospital
50% at 4 w
Malnutrition
 Hennart et al 14 Every year for 5 years15.959% at 52 w
 Kerac et al 12 23.290 days and 1 year17.26.6224.044% at 13 w
 Chisti et al 13 8.6Weekly for 2 weeks then monthly until 6 months15.08.780% at home
16% in hospital
4% on transport
59% at 4 w
88% at 9 w
 Berkley et al 15 Oral cotrimoxazole prophylaxis3.4Once per month until 6 months, then once every 2 months until 12 months5.3296 non-fatal admissions11.1(32%) in readmission to a study hospital
(15%) in other hospitals
(53%) in the community
Placebo5.1320 non-fatal admissions
 Grenov et al 32 Probiotics11.5At 8–12 weeks10.41.8
Placebo8.07.92.4
Respiratory infection
 West et al 33 HypoxaemiaMean length of follow-up 41 months36.19.6
Non-hypoxaemicMean length of follow-up 34.1 months39.33.7
 Villamor et al 17 3.1Every 2 weeks for a year then every 4 months
Mean duration of follow-up 24.7 months (SD=12.3, median=28.2)
11.410.480% by 52 w
 Ashraf et al 34 0Every 2 weeks for 3 months6.46.41.7
 Reddy et al 35 Standard and intensified diagnostic arms analysed together2 and 8 weeks post-enrolment17.450% at 2 w
‘postenrolment deaths’; IP or PD not specified
 Chhibber et al 16 3.9180 days2.855% at 6 w
 Ngari et al 18 Pneumonia5.6Every 4 months until 1 year1.93.137% in hospital44% at 13 w
74% at 26 w
No pneumonia2.40.91.3
 Newberry et al 36 Corticosteroids27.81, 3, 6 months11.519.2
Placebo52.410.035.0
Diarrhoeal diseases
 Roy et al 19 Monthly for 12 months452% at 4 w
70% at 9 w
 Stanton et al 37 1.8At 4–5 months6.82.9
 Islam et al 20 14.6At 6 and 12 weeks7.594% at 6 w
Anaemia/Malaria
 Zucker et al 24 Anaemia134 and 8 weeks4.018.8
No anaemia; figures include the analysed ‘no-anaemia cohort’ from study plus additional children94.010.3
 Biai et al 21 Intervention: improved management and free emergency drugs for malaria, financial incentive4.628 days3.91.8
Control9.44.90.9
 Phiri et al 25 Severe anaemia6.41, 3, 6, 12, 18 months17.818.111.671% at 26 w
No anaemia019.69.32.760% at 26 w
 Phiri et al 23 Artemether–lumefantrine1, 3, 6 months5.021.52.550% at 4 w
Placebo4.924.42.350% at 9 w
 Olupot-Olupot et al 26 Severe anaemia—higher blood transfusion volume (30 mL/kg)028 days postadmission01.3
Severe anaemia—standard blood transfusion volume (20 mL/kg)7.300
 Opoka et al 22 Cerebral malaria12.66 months2.53.10.6
Severe malarial anaemia0.43.69.42.2
  • *Indicates cumulative rates as of the last follow-up time.

  • †Indicates specified mortality statistics in regard to per cent of total postdischarges by a certain number of weeks, in relation to entire duration of follow-up.

  • IP, inpatient; IPM, inpatient mortality; PD, postdischarge; PDM, postdischarge mortality; w,week.