Comorbidity | Comorbidities at SICSAG admission | New comorbidities developed after discharge | |||||||
% of AP cohort | % of controls | P value | % of AP cohort | % of controls | P value | OR | 95% CI lower | 95% CI upper | |
AMI | 2.7 | 1.2 | <0.001 | 3.7 | 1.8 | <0.001 | 2.09 | 1.4 | 3.12 |
Cerebral vascular accident | 1.9 | 1.7 | 0.555 | 3.5 | 2.2 | 0.021 | 1.58 | 1.07 | 2.35 |
Congestive heart failure | 2.3 | 0.4 | <0.001 | 2.5 | 0.8 | <0.001 | 3.11 | 1.83 | 5.28 |
Connective tissue disorder | 0.8 | 0.3 | 0.024 | 0.1 | 0.1 | 0.641 | 0.6 | 0.07 | 5.16 |
Diabetes and diabetes complications | 1.8 | 0.2 | <0.001 | 3.9 | 0.4 | <0.001 | 10.7 | 5.74 | 19.94 |
Liver disease and severe liver disease | 0.5 | 0.1 | 0.004 | 0.6 | 0.1 | 0.003 | 5.3 | 1.55 | 18.14 |
Peptic ulcer | 1.9 | 0.3 | <0.001 | 1.6 | 0.3 | <0.001 | 5.06 | 2.38 | 10.74 |
Peripheral vascular disease | 1.5 | 0.6 | 0.007 | 1.3 | 0.5 | 0.002 | 2.86 | 1.41 | 5.81 |
Pulmonary disease | 3.8 | 1.1 | <0.001 | 2.5 | 1.6 | 0.033 | 1.65 | 1.04 | 2.62 |
Cancer and metastatic cancer | 7.2 | 2.8 | <0.001 | 8.4 | 5.4 | <0.001 | 1.62 | 1.25 | 2.11 |
Renal disease | 1 | 0.2 | 0.001 | 1.1 | 0.1 | <0.001 | 9.15 | 2.95 | 28.43 |
The percentage of patients and controls who developed each specified comorbidity in the 5 years before and 5 years after the index AP episode is presented. The OR as well as the 95% CI for the development of each comorbidity after the AP episode are included. Total number of patients from the AP cohort: 1150; total number of controls: 3450. The p values were obtained by applying the two-sample z test. P<0.05 was considered significant.
AMI, acute myocardial infarction; AP, acute pancreatitis; SICSAG, Scottish Intensive Care Society Audit Group software; OR, odds ratio.