Table 1

Baseline data of tested traits and tested SNPs

TraitMean±SD or quartilesN of subjects (male/female)N of SNPs reported*N of SNPs tested*Covariates
ACR (mg/mmol) 1.05/3.9/12.7†115 (56/59)33183Age and gender.
Vitamin D (ng/mL) 63.7±27.8328 (146/182)44292Age and gender.
eGFR (ml/min/1.73 m2) 81.5±28.5395 (172/223)1478288Age and gender.
Serum creatinine (µmol/L) 60/74/95.8†474 (246/228)1792363Age and gender.
Blood urea (mmol/L) 6.4±5.4450 (263/214)44673Age and gender.
Diabetic kidney disease With: 145.
Without: 265.
28863Age, gender, hypertension, T2DM duration and eGFR levels.
  • *Reported means the total number of SNPs found in the search in the literature and tested means the actual number of SNPs found from the reported SNPs and used for the analyses in this study for each corresponding trait.

  • †For the albumin:creatinine ratio (ACR) and creatinine analyses, summary statistics indicated by 25th/50th/75th quartiles and not as mean±SD because their distributions are skewed.

  • eGFR, estimated glomerular filtration rate; SNPs, single nucleotide polymorphisms; T2DM, type 2 diabetes mellitus.