Demographic data of OIRD
| Study ID et al (country) | Total patients (n) | Total OIRD n (%) | OIRD within 12 hours—n (%) | OIRD within 24 hours—n (%) | OIRD group | ||
| Age (year) | Women(n) | BMI (kg/m2) | |||||
| Etches6 (Canada) | 1600 | 11 (0.69) | 6 (55%) | 9 (82) | 55±16 | 3 | NA |
| Gordon and Pellino14 (USA) | 10 511 | 44 (0.53) | NA | 25 (57) | 60±16 | 36 | NA |
| Shapiro et al
13 (Israel) | 1524 | 18 (1.18) | NA | NA | 51±24 | 14 | 25.4±6.5 |
| Taylor et al
5 (USA) | - | 62 | 35 (56) | 48 (77) | 68±16 | 38 | NA |
| Overdyk et al
12 (USA) | 178 | 73 (41) | NA | NA | NA | NA | NA |
| Ramachandran et al
11 (USA) | 85 650 | 32 (0.04) | NA | 27 (84) | 52±17 | 18 | 32.5±9.2 |
| Khelemsky et al
9 (USA) | 442 699 | 433 (0.10) | NA | NA | 60±16 | 260 | 27±7 |
| Lee et al
10 (USA) | 9799 claims | 92 claims | NA | 81 (88) | 50±18 | 52 | NA |
| Weingarten et al
8 (USA) | 84 533 | 134 (0.16) | 78 (58) | 110 (82) | 65±15 | 78 | 28.9±6.8 |
| Weingarten et al
7 (USA) | 11 970 | 2836 (23.70) | 2836 (100) | 2836 (100) | 65±12 | 1434 | 31±6 |
| Rosenfeld et al
3 (USA) | 28 151 | 108 (0.38) | NA | 66 (61) | 64±16 | 56 | NA |
| Weingarten et al
4 (USA) | 164 809 | 413 (0.25) | 413 (100) | 413 (100) | 61±16 | 221 | 28±7 |
| Total n (%) | 841 424 | 4194 (0.5) | 3333 (0.4) | 3567 (0.42) | 58±6 | 2210 | 28.8±3 |
BMI, body mass index; n, number; NA, not applicable; OIRD, opioid-induced respiratory depression.