All prescriptions | LRTI prescriptions | ||||||||||||
B/N ratio | P values | AI | P values | A/B ratio | P values | B/N ratio | P values | AI | P value | A/B ratio | P values | ||
IPCI | Asthma | 4.7 | Ref. | 34.7% | Ref. | 1.1 | Ref. | 23.3 | Ref. | 48.6% | Ref. | 1.2 | Ref. |
No asthma | 3.2 | <0.0001 | 31.5% | <0.0001 | 1.1 | 0.0054 | 20.6 | 0.5576 | 50.3% | 0.3512 | 1.3 | 0.4074 | |
THIN | Asthma | 0.4* | Ref. | 38.8%† | ref. | 3.8* | Ref. | 0.6* | Ref. | 72.8%* | Ref. | 7.6* | Ref. |
No asthma | 0.3* | <0.0001 | 33.7%* | <0.0001 | 4.0* | <0.0001 | 0.5* | <0.0001 | 73.2%* | <0.0001 | 8.6* | <0.0001 |
B/N ratio: J01CR J01DC, J01DD, J01F (except J01FA01)/J01CE, J01DB, J01FA01.
AI: J01CA04/J01.
A/B ratio: J01CA04/J01CR, J01DC, J01DD, J01F (except J01FA01).
J01CA04, amoxicillin; J01CE, beta-lactamase sensitive penicillins; J01CR, combinations of penicillins; J01DB, first-generation cephalosporins; J01DC, second-generation cephalosporins; JOIDD, third-generation cephalosporins; J01F, macrolides, lincosamides and streptogramins; J01FA01, erythromycin.
*Significant different from IPCI cohort, p<0.0001.
†Significant different from IPCI cohort, p<0.005.
A/B, amoxicillin/broad ratio; AI, Amoxicillin Index; B/N, broad/narrow ratio; IPCI, Integrated Primary Care Information database; LRTI, lower respiratory tract infection; THIN, The Health Improvement Network; Ref., reference.