SCRUM sample collection schema
| Test | Time point | ||||
| Baseline | Pitch-side | Postmatch | 36–48 hours postinjury | Stage V GRTP | |
| Concussed player | |||||
| HIA | X | X (HIA1) | X (HIA2) | X (HIA3) | |
| Saliva | X | X | X | X | X |
| Urine | X | X | X | X | |
| Orthopaedic control player | |||||
| HIA | X | ||||
| Saliva | X | X | X | ||
| Urine | X | X | X | ||
| Uninjured player | |||||
| HIA | X | ||||
| Saliva | X | X | X | ||
| Urine | X | X | X | ||
GRTP, Graduated Return-to-Play protocol; HIA, Head Injury Assessment protocol; SCRUM, Study of Concussion in Rugby Union through MicroRNAs.