Characteristics of the study subjects
| Variable | NTG group n=15 317 | Comparison group n=61 268 | P values |
| n (%) | n (%) | ||
| Age, year, (mean±SD) | 62.1±12.5 | 62.1±12.5 | 1.000 |
| Age, categorical | 1.000 | ||
| <55 | 4778 (31.2) | 19 112 (31.2) | |
| 55–65 | 3889 (25.4) | 15 556 (25.4) | |
| 65–75 | 3627 (23.7) | 14 508 (23.7) | |
| ≥75 | 3023 (19.7) | 12 092 (19.7) | |
| Gender | 1.000 | ||
| Male | 8372 (54.7) | 33 488 (54.7) | |
| Female | 6945 (45.3) | 27 780 (45.3) | |
| Comorbidities | |||
| Diabetes | 5110 (33.4) | 15 671 (25.6) | <0.0001 |
| Hypertension | 9148 (59.7) | 32 790 (53.5) | <0.0001 |
| Hyperlipidaemia | 7590 (49.6) | 21 628 (35.3) | <0.0001 |
| Coronary artery disease | 5627 (36.7) | 16 323 (26.6) | <0.0001 |
| Stroke | 1572 (10.3) | 6518 (10.6) | 0.18 |
| Follow-up period, year (mean±SD) | 4.92±3.29 | 4.96±3.27 | 0.18 |
| Occurrence of AD during the follow-up period | 1023 (6.7) | 2574 (4.2) | <0.0001 |
AD, Alzheimer’s disease; NTG, normal tension glaucoma.