Table 2

Haematological profile of study population overall and by CKD (MDRD and CKD-EPI) status

VariablesTotal (n=1564)MDRDCKD-EPI
Without CKD
(n=1470)
CKD
(n=94)
P valuesWithout CKD
(n=1517)
CKD
(n=47)
P values
RBC (x1012/L)4.7 (4.3–5.0)4.7 (4.4–5.0)4.3 (3.9–4.7)<0.00014.7 (4.4–5.0)4.2 (3.8–4.7)<0.0001
WBC (x109/L)7.5 (6.2–9.1)7.4 (6.2–9.1)7.7 (6.5–9.2)0.57047.4 (6.2–9.1)7.9 (6.3–9.3)0.5458
 N/L (ratio)2.0 (1.5–2.6)1.9 (1.5–2.5)2.5 (1.7–3.5)<0.00011.9 (1.5–2.5)2.7 (2.0–3.7)<0.0001
 Lymphocyte count (x109/L)2.2 (1.8–2.80)2.2 (1.8–2.8)1.9 (1.4–2.5)0.00012.2 (1.8–2.8)1.8 (1.4–2.4)<0.0001
 Monocyte count (x109/L)0.5 (0.4–0.6)0.5 (0.4–0.6)0.4 (0.4–0.6)0.13890.5 (0.4–0.6)0.4 (0.4–0.6)0.9446
 Neutrophil count (x109/L)4.5 (3.4–5.7)4.5 (3.3–5.6)5.0 (3.7–5.9)0.02554.5 (3.4–5.6)5.1 (4.3–6.1)0.0297
 Basophil count (x109/L)0.1 (0.1–0.2)0.0 (0.0–0.0)0.0 (0.0–0.1)0.2830.0 (0.0–0.0)0.0 (0.0–0.1)0.1366
 Eosinophil count (x109/L)0.2 (0.1–0.3)0.2 (0.1–0.3)0.2 (0.1–0.3)0.15790.2 (0.1–0.3)0.2 (0.1–0.3)0.1223
Platelet count (x109/L)271 (227–322)271 (228–322)277 (214–324)0.9417271 (228–322)266 (197–313)0.2211
Haematocrit (volume %)41 (39–44)41 (39–44)38 (35–41)<0.000141 (39–44)37 (34–41)<0.0001
MCV (fl/cell)89 (85–93)89 (85–93)89 (86–92)0.815089 (85–93)89 (86–91)0.4748
MCH (pg/cell)29 (28–31)29 (28–31)29 (28–30)0.139929 (28–31)29 (28–30)0.057
MCHC (g/dL)33 (32–33)33 (32–33)33 (32–33)0.147133 (32–33)32 (32–33)0.1156
RDW (%)14.2 (13.5–15.0)14.1 (13.4–15.0)14.5 (13.7–15.6)0.060114.1 (13.4–15.0)14.3 (13.8–15.5)0.0673
Hb (g/dL)13.5 (12.6–14.4)13.5 (12.7–14.5)12.2 (11.2–13.3)<0.000113.5 (12.6–14.4)11.9 (11.1–13.2)<0.0001
Anaemia, n (%)289 (18.48)249 (16.9)40 (45.5)<0.0001263 (17.3)26 (57.8)<0.0001
 Microcytic83 (28.7)83 (33.3)0 (0.0)83 (31.6)0 (0.0)
 Normocytic180 (62.3)141 (56.6)39 (97.5)155 (58.9)25 (96.2)
 Macrocytic26 (9.0)25 (10.0)1 (2.5)25 (9.5)1 (3.8)
  • Data are presented as median (25th-75th percentiles) and percentages.

  • CKD, chronic kidney disease; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; Hb, haemoglobin; MCH, mean corpuscular Hb; MCHC, MCH concentration; MCV, mean corpuscular volume; MDRD, Modification of Diet in Renal Disease; N/L ratio, lymphocyte to neutrophil ratio; RBC, red blood cells; RDW, red cell distribution width; WBC, white blood cells.